ArrayExpress Uploader04961464KIT mutation: wildtypestomachfemale2150KIT mutation: wildtypestomachmale1251KIT mutation: Exon 11stomachmale671KIT mutation: Exon 11stomachmale1363KIT mutation: Exon 11stomachfemale752KIT mutation: Exon 11stomachmale681KIT mutation: Exon 11stomachmale441KIT mutation: Exon 11stomachfemale552KIT mutation: wildtypestomachfemale2572KIT mutation: Exon 11stomachfemale1768KIT mutation: Exon 11stomachmale464KIT mutation: wildtypestomachfemale861KIT mutation: wildtypestomachmale769KIT mutation: wildtypestomachmale447KIT mutation: Exon 11stomachmale1171KIT mutation: Exon 11stomachmale1968KIT mutation: Exon 11stomachmale1054KIT mutation: Exon 11stomachmale3856KIT mutation: Exon 11stomachmale1040KIT mutation: Exon 11stomachfemale1358KIT mutation: Exon 11stomachmale655KIT mutation: wildtypestomachfemale2069KIT mutation: Exon 11stomachfemale361KIT mutation: Exon 9small intestinefemale468KIT mutation: Exon 9small intestinemale477KIT mutation: wildtypesmall intestinemale776KIT mutation: Exon 11small intestinemale1834KIT mutation: Exon 11small intestinemale768KIT mutation: Exon 9small intestinemale482KIT mutation: Exon 9small intestinemale1261KIT mutation: Exon 11small intestinefemale668KIT mutation: wildtypesmall intestinefemalearrayexpress_sid4GIST is considered to invariably arise through gain-of-function KIT or PDGFRA mutation of the interstitial cells of Cajal (ICC). However,...18757323E-GEOD-8167/profile/8773/arrayexpressuploader532genomegistintestinesmall intestinestomachDec.12, 2014Falsetranscription-profiling-by-array-of-human-gastro-2E-GEOD-8167_A-AFFY-44Transcription profiling by array of human gastrointestinal stromal tumors with KIT mutationsSep.22, 2014GIST is considered to invariably arise through gain-of-function KIT or PDGFRA mutation of the interstitial cells of Cajal (ICC). However, the genetic basis of the malignant progression of GIST is poorly understood. We analysed the expression levels of 54,613 probe sets in 32 surgical samples of untreated GIST of the stomach and small intestine with GeneChip Human Genome U133 Plus 2.0 arrays. Experiment Overall Design: Total RNA was extracted from 32 fresh frozen tumour specimens. We analysed the global gene exprssion profiles of these GIST cases in order to clarify the genomic basis behind the malignant progression of this tumorhttp://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-8167humanhttp://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-8167/samples/