{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "human", "factors": [{"GSE7904GSM194416": {}}, {"GSE7904GSM194417": {}}, {"GSE7904GSM194415": {}}, {"GSE7904GSM194418": {}}, {"GSE7904GSM194407": {}}, {"GSE7904GSM194397": {}}, {"GSE7904GSM194412": {}}, {"GSE7904GSM194409": {}}, {"GSE7904GSM194414": {}}, {"GSE7904GSM194404": {}}, {"GSE7904GSM194398": {}}, {"GSE7904GSM194413": {}}, {"GSE7904GSM194399": {}}, {"GSE7904GSM194400": {}}, {"GSE7904GSM194410": {}}, {"GSE7904GSM194408": {}}, {"GSE7904GSM194401": {}}, {"GSE7904GSM194402": {}}, {"GSE7904GSM194403": {}}, {"GSE7904GSM194405": {}}, {"GSE7904GSM194411": {}}, {"GSE7904GSM194406": {}}, {"GSE7904GSM194421": {}}, {"GSE7904GSM194420": {}}, {"GSE7904GSM194427": {}}, {"GSE7904GSM194426": {}}, {"GSE7904GSM194438": {}}, {"GSE7904GSM194425": {}}, {"GSE7904GSM194422": {}}, {"GSE7904GSM194423": {}}, {"GSE7904GSM194419": {}}, {"GSE7904GSM194428": {}}, {"GSE7904GSM194430": {}}, {"GSE7904GSM194429": {}}, {"GSE7904GSM194434": {}}, {"GSE7904GSM194435": {}}, {"GSE7904GSM194439": {}}, {"GSE7904GSM194433": {}}, {"GSE7904GSM194436": {}}, {"GSE7904GSM194424": {}}, {"GSE7904GSM194432": {}}, {"GSE7904GSM194431": {}}, {"GSE7904GSM194437": {}}, {"GSE7904GSM194452": {}}, {"GSE7904GSM194453": {}}, {"GSE7904GSM194454": {}}, {"GSE7904GSM194455": {}}, {"GSE7904GSM194456": {}}, {"GSE7904GSM194457": {}}, {"GSE7904GSM194458": {}}, {"GSE7904GSM194441": {}}, {"GSE7904GSM194449": {}}, {"GSE7904GSM194442": {}}, {"GSE7904GSM194443": {}}, {"GSE7904GSM194444": {}}, {"GSE7904GSM194445": {}}, {"GSE7904GSM194446": {}}, {"GSE7904GSM194447": {}}, {"GSE7904GSM194450": {}}, {"GSE7904GSM194448": {}}, {"GSE7904GSM194451": {}}, {"GSE7904GSM194440": {}}], "id": 4947, "ownerprofile_id": "arrayexpress_sid", "platform": 4, "summary_wrapped": "bulk breast tumor RNA from patient; Abstract: Sporadic basal-like cancers (BLC) are a distinct class of human breast cancers that are...", "geo_gse_id": "E-GEOD-7904", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 0, "sample_count": 62, "tags": ["basal", "brca1", "breast", "breast tumor", "chromosome", "class", "organelle", "x chromosome"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "transcription-profiling-of-human-breast-tissue-tum", "geo_id_plat": "E-GEOD-7904_A-AFFY-44", "name": "Transcription profiling of human breast tissue tumors vs. normal tissue", "created": "Sep.22, 2014", "summary": "bulk breast tumor RNA from patient; Abstract: Sporadic basal-like cancers (BLC) are a distinct class of human breast cancers that are phenotypically similar to BRCA1-associated cancers. Like BRCA1-deficient tumors, most BLC lack markers of a normal inactive X chromosome (Xi). Duplication of the active X chromosome and loss of Xi characterized almost half of BLC cases tested. Others contained biparental but nonheterochromatinized X chromosomes or gains of X chromosomal DNA. These abnormalities did not lead to a global increase in X chromosome transcription but were associated with overexpression of a small subset of X chromosomal genes. Other, equally aneuploid, but non-BLC rarely displayed these X chromosome abnormalities. These results suggest that X chromosome abnormalities contribute to the pathogenesis of BLC, both inherited and sporadic. total 62 sample incudes 43 tumor, 7 normal breast and  12 normal organelle Experiment Overall Design: compare expression of tumor to normal breast tissue", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-7904", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-7904/samples/"}