Dataset: Transcription profiling by array of lungs from mice mutant for RAG after challenge with ovalbumin
Experimental asthma was induced in BALB/c mice by sensitization and challenge with the allergen ovalbumin. Control groups received PBS....
Experimental asthma was induced in BALB/c mice by sensitization and challenge with the allergen ovalbumin. Control groups received PBS. To investigate the innate immune component of experimental asthma, we also analyzed recombinase activating gene (RAG) deficient mice following exposure to ovalbumin and control PBS Experiment Overall Design: Each experimental group was exposed to ovalbumin or control PBS. At day 22, 1 day after completion of the allergen exposure, whole lungs were harvested, total mRNA prepared, and gene expression determined by hybridization to Affymetrix microarrays.
- Species:
- mouse
- Samples:
- 16
- Source:
- E-GEOD-6858
- PubMed:
- 17437023
- Updated:
- Dec.12, 2014
- Registered:
- Nov.13, 2014
Factors:
(via ArrayExpress)
| Sample | dose | genotype | compound |
|---|---|---|---|
| GSE6858GSM158134 | 10 | RAG null mutant | ovalbumin |
| GSE6858GSM158134 | 10 | RAG null mutant | ovalbumin |
| GSE6858GSM158134 | 10 | RAG null mutant | ovalbumin |
| GSE6858GSM158134 | 10 | RAG null mutant | ovalbumin |
| GSE6858GSM158132 | RAG null mutant | none | |
| GSE6858GSM158132 | RAG null mutant | none | |
| GSE6858GSM158132 | RAG null mutant | none | |
| GSE6858GSM158132 | RAG null mutant | none | |
| GSE6858GSM158138 | 10 | wild type | ovalbumin |
| GSE6858GSM158138 | 10 | wild type | ovalbumin |
| GSE6858GSM158138 | 10 | wild type | ovalbumin |
| GSE6858GSM158138 | 10 | wild type | ovalbumin |
| GSE6858GSM158136 | wild type | none | |
| GSE6858GSM158136 | wild type | none | |
| GSE6858GSM158136 | wild type | none | |
| GSE6858GSM158136 | wild type | none |