{"owner": "ArrayExpress Uploader", "ownerprofile_id": "arrayexpress_sid", "id": 7763, "factors": [{"GSE6681GSM154369": {}}, {"GSE6681GSM154373": {}}, {"GSE6681GSM154366": {}}, {"GSE6681GSM154371": {}}], "pop_total": 0, "platform": 6, "summary_wrapped": "Analysis of Foxp3 ablated peripheral regulatory T cells. Regulatory T cells require the expression of the transcription factor Foxp3 for...", "pubmed_id": 17220892, "geo_gse_id": "E-GEOD-6681", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 0, "sample_count": 4, "tags": ["cell", "peripheral", "protein"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_id_plat": "E-GEOD-6681_A-AFFY-45", "slug": "transcription-profiling-of-mouse-foxp3-ablation-in", "geo_gds_id": "", "name": "Transcription profiling of mouse Foxp3 ablation in peripheral mature regulatory T cells", "created": "Nov.13, 2014", "summary": "Analysis of Foxp3 ablated peripheral regulatory T cells. Regulatory T cells require the expression of the transcription factor Foxp3 for thymic development. It is not known whether continuous expression of Foxp3 is required for the maintained function of mature regulatory T cells in the periphery. Results indicate changes to the regulatory T cell developmental program in the absence of Foxp3. Experiment Overall Design: Compare Cre recombinase treated peripheral regulatory T cells possessing a Cre sensitive Foxp3 locus to Cre treated regulatory T cells with a wild type Foxp3 locus. Cre exposure is observed via the Cre sensitive expression of the yellow flourescent protein molecule.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-6681", "species": "mouse", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-6681/samples/"}