ArrayExpress Uploader0humanempty pFB vectorempty pFB vectorempty pFB vectorFGFR3 mutation S249CFGFR3 mutation S249CFGFR3 mutation S249C4823arrayexpress_sid4Activating mutations of FGFR3 are found in a high proportion of bladder tumours. The molecular consequences of FGFR3 mutation in...E-GEOD-61352/profile/8773/arrayexpressuploader16Dec.12, 2014Falseexpression-data-from-normal-urothelial-cells-withE-GEOD-61352_A-AFFY-44Expression data from normal urothelial cells with exogenous expression of mutant FGFR3Sep.21, 2014Activating mutations of FGFR3 are found in a high proportion of bladder tumours. The molecular consequences of FGFR3 mutation in urothelial cells and the mechanisms by which mutant FGFR3 may drive bladder tumourigenesis are largely unknown. We used expression arrays to identify downstream targets of mutant FGFR3 signalling in normal urothelial cells. TERT-immortalized normal urothelial cells stably transduced to express the most common FGFR3 mutation (S249C) were compared with control cells transduced with the empty vector (pFB).http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-61352http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-61352/samples/