ArrayExpress Uploader0humannot specifiedundifferentiated embryonic stem cellsnot specifiedcontroldifferentiated embryonic stem cellsday 3MGCDdifferentiated embryonic stem cellsday 3controldifferentiated embryonic stem cellsday 7MGCDdifferentiated embryonic stem cellsday 74820arrayexpress_sid4Mocetinostat (MGCD) which is a kind of histone deacetylase inhibitors (HDACi) promotes human embryonic stem cells (hESCs) differentiation...E-GEOD-61050/profile/8773/arrayexpressuploader35histoneDec.12, 2014FalseE-GEOD-61050_A-AFFY-44expression-data-of-neural-progenitor-cells-differeExpression data of neural progenitor cells differentiation from human embryonic stem cellsSep.21, 2014Mocetinostat (MGCD) which is a kind of histone deacetylase inhibitors (HDACi) promotes human embryonic stem cells (hESCs) differentiation towards neural progenitor cells (NPCs). Application of HDAC inhibitors (HDACi) increased the expression of neuroectodermal markers once neural differentiation was initiated, thereby leading to more NPC generation. We used microarrays to detail the global gene expression during NPC differentiaton upon MGCD treatment and identified the transcript changes effected by MGCD during this process. Undifferentiated H9 hESCs (D0), as well as H9 cells with or without MGCD treatment on day 3 (D3C and D3M) and on day 7(D7C and D7M) of NPC generation were collected for RNA extraction and hybridization on Affymetrix microarrays.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-61050http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-61050/samples/