6ArrayExpress Uploaderarrayexpress_sidmouseoverexpressed vector controloverexpressed vector controloverexpressed vector controloverexpressed Foxd3overexpressed Foxd3overexpressed Foxd3overexpressed CA-NFATc3overexpressed CA-NFATc3overexpressed CA-NFATc3overexpressed Foxd3 and CA-NFATc3overexpressed Foxd3 and CA-NFATc3overexpressed Foxd3 and CA-NFATc3Foxd3 conditional knockout cells treated with DMSOFoxd3 conditional knockout cells treated with DMSOFoxd3 conditional knockout cells treated with DMSOFoxd3 conditional knockout cells treated with TamoxifenFoxd3 conditional knockout cells treated with TamoxifenFoxd3 conditional knockout cells treated with Tamoxifen76690http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-58960Pluripotency-associated transcription factor Foxd3 is required for maintaining pluripotent cells. However, the molecular mechanisms.../profile/8773/arrayexpressuploader118Dec.12, 2014Falseexpression-data-from-embryonic-stem-cells-differenE-GEOD-58960_A-AFFY-45Expression data from embryonic stem cells differentiationNov.12, 2014Pluripotency-associated transcription factor Foxd3 is required for maintaining pluripotent cells. However, the molecular mechanisms underlying its function are largely unknown. Here, we report that Foxd3 maintains the ESC identity through counteracting differentiation induction of Calcienurin-NFAT signaling. We used microarrays to detail the global programme of gene expression underlying overexpression of Foxd3 and NFATc3 in ESCs or deletion of Foxd3 in ESCs Total RNA was extracted from the mESCs under the following conditions:1) a control group transfected with an empty vector; a Foxd3 overexpression group; a NFATc3 overexpression group and a combination group with Foxd3 and NFATc3 overexpression 2) Foxd3fl/fl:Cre-ERT cells treated with Tamoxifen for 0 day and 2 days.E-GEOD-58960http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-58960/samples/