{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "mouse", "factors": [{"GSM1407132": {"BACKGROUND STRAIN": "C57BL6", "GENOTYPE": "wildtype"}}, {"GSM1407132": {"BACKGROUND STRAIN": "C57BL6", "GENOTYPE": "wildtype"}}, {"GSM1407132": {"BACKGROUND STRAIN": "C57BL6", "GENOTYPE": "wildtype"}}, {"GSM1407135": {"BACKGROUND STRAIN": "C57BL6", "GENOTYPE": "homozygous Leiden"}}, {"GSM1407135": {"BACKGROUND STRAIN": "C57BL6", "GENOTYPE": "homozygous Leiden"}}, {"GSM1407135": {"BACKGROUND STRAIN": "C57BL6", "GENOTYPE": "homozygous Leiden"}}, {"GSM1407138": {"BACKGROUND STRAIN": "BALB/c", "GENOTYPE": "wildtype"}}, {"GSM1407138": {"BACKGROUND STRAIN": "BALB/c", "GENOTYPE": "wildtype"}}, {"GSM1407138": {"BACKGROUND STRAIN": "BALB/c", "GENOTYPE": "wildtype"}}, {"GSM140714": {"BACKGROUND STRAIN": "BALB/c", "GENOTYPE": "homozygous Leiden"}}, {"GSM1407142": {"BACKGROUND STRAIN": "C57BL6", "GENOTYPE": "heterozygous Leiden"}}, {"GSM1407142": {"BACKGROUND STRAIN": "C57BL6", "GENOTYPE": "heterozygous Leiden"}}, {"GSM1407142": {"BACKGROUND STRAIN": "C57BL6", "GENOTYPE": "heterozygous Leiden"}}, {"GSM1407142": {"BACKGROUND STRAIN": "C57BL6", "GENOTYPE": "heterozygous Leiden"}}], "id": 7659, "ownerprofile_id": "arrayexpress_sid", "platform": 6, "summary_wrapped": "We investigated in mouse models how enhanced coagulation activation due to a common disease polymorphism in coagulation factor V (fV...", "geo_gse_id": "E-GEOD-58328", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 2, "sample_count": 14, "tags": ["bone", "bone marrow", "dendritic", "disease", "lipopolysaccharide", "macrophage", "spleen"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "expression-data-from-mouse-spleen-cd11c-dendritic", "geo_id_plat": "E-GEOD-58328_A-AFFY-45", "name": "Expression data from mouse spleen CD11c dendritic cells, bone marrow Gr1DC11b cells, and RAW264.7 cells", "created": "Nov.12, 2014", "summary": "We investigated in mouse models how enhanced coagulation activation due to a common disease polymorphism in coagulation factor V (fV Leiden Arg506Gln) modifies the host response to infection and inflammation We used microarrays to characterize the in vivo and in vitro inflammatory responses of mouse spleen dendritic cells, macrophage-like RAW264.7 cells, and bone marrow myeloid cells Samples 1-6 were generated by pooling equal amounts of RNA prepared from FACS-enriched spleen dendritic cells isolated from 6 individual mice before (control sample 1) or 16 hours after challenge with lipopolysaccharide. Samples 7-10 were generated by pooling equal amounts of RNA prepared from triplicate cultures of RAW264.7 cells. Samples 10-14 (2 replicas per condition) were prepared from RNA isolated from FACS-enriched bone marrow myeloid cells (pooled from 4 adoptively transferred animals each) 7 days after infection with S.aureus.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-58328", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-58328/samples/"}