{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "mouse", "factors": [{"GSM1390726": {"TREATMENT": "DMSO"}}, {"GSM1390726": {"TREATMENT": "DMSO"}}, {"GSM1390726": {"TREATMENT": "DMSO"}}, {"GSM1390726": {"TREATMENT": "DMSO"}}, {"GSM1390726": {"TREATMENT": "DMSO"}}, {"GSM1390726": {"TREATMENT": "DMSO"}}, {"GSM1390732": {"TREATMENT": "JQ1"}}, {"GSM1390732": {"TREATMENT": "JQ1"}}, {"GSM1390732": {"TREATMENT": "JQ1"}}, {"GSM1390735": {"TREATMENT": "MLN8237"}}, {"GSM1390735": {"TREATMENT": "MLN8237"}}, {"GSM1390735": {"TREATMENT": "MLN8237"}}], "id": 7641, "ownerprofile_id": "arrayexpress_sid", "platform": 6, "summary_wrapped": "Amplification of MYCN is the most prominent genetic marker of high-stage neuroblastoma, a childhood tumor originating from the neural...", "geo_gse_id": "E-GEOD-57810", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 1, "sample_count": 12, "tags": ["cell", "crest", "line", "neural crest", "neuroblastoma"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "expression-profiling-tumor-cells-from-mycn-driven", "geo_id_plat": "E-GEOD-57810_A-AFFY-45", "name": "Expression profiling tumor cells from MYCN-driven neuroblastoma upon BRD4 or AURKA inhibition", "created": "Nov.12, 2014", "summary": "Amplification of MYCN is the most prominent genetic marker of high-stage neuroblastoma, a childhood tumor originating from the neural crest. We generated a cell line (mNB-A1) from tumors developed in transgenic mouse and treated these cells with DMSO (n=6), the BRD4-inhibitor JQ1 (n=3) or the AURKA-inhibitor MLN8237 (n=3) for 24 h. The expression profiles of vehicle (DMSO)-treated mNB-A1 cells were compared to JQ1- or MLN8237-treated mNB-A1 cells.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-57810", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-57810/samples/"}