{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "mouse", "factors": [{"GSM1384372": {"GENOTYPE": "WT"}}, {"GSM1384372": {"GENOTYPE": "WT"}}, {"GSM1384372": {"GENOTYPE": "WT"}}, {"GSM1384375": {"GENOTYPE": "miR-142 KO"}}, {"GSM1384375": {"GENOTYPE": "miR-142 KO"}}, {"GSM1384375": {"GENOTYPE": "miR-142 KO"}}], "id": 7637, "ownerprofile_id": "arrayexpress_sid", "platform": 6, "summary_wrapped": "T cells are critical for modulating immune responses. miRNAs are  small, noncoding RNAs and play a significant role in T cell responses....", "geo_gse_id": "E-GEOD-57543", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 1, "sample_count": 6, "tags": ["cell"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "expression-data-from-b6-mouse-mir-142-ko-and-wt-t", "geo_id_plat": "E-GEOD-57543_A-AFFY-45", "name": "Expression data from B6 mouse miR-142 KO and WT T cells", "created": "Nov.12, 2014", "summary": "T cells are critical for modulating immune responses. miRNAs are  small, noncoding RNAs and play a significant role in T cell responses. miR-142 is a hematopoietic specific miRNA. To explore the potential role of miR-142  in regulating T cell responses, we generated mutant mice bearing a targeted deletion of the miR-142 gene. We used microarrays to detail the global programme of gene expression underlying the profile changes between miR-142 KO and WT T cell and identified distinct classes of up-regulated genes during this process. miR-142 KO mice and WT littermates (biological triplicates) matched with age and sex were selected. T cells were purified from spleens by negative selection and processed for RNA isolation and hybridization on Affymetrix microarrays.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-57543", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-57543/samples/"}