ArrayExpress Uploader0humanvehicleFlavopiridolFIT-0392710arrayexpress_sid4FIT-039 is a novel antiviral compound. Antiviral mechanism of FIT-039 is the inhibition of the viral transcription through suppression of...E-GEOD-57429/profile/8773/arrayexpressuploader13Dec.12, 2014Falseexpression-data-from-fit-039-or-flavopiridol-compoE-GEOD-57429_A-AFFY-44Expression data from FIT-039 or Flavopiridol compound treated HeLa cellsJul.22, 2014FIT-039 is a novel antiviral compound. Antiviral mechanism of FIT-039 is the inhibition of the viral transcription through suppression of the CTD phosphorylation of RNA polymerase II. We used microarrays to evaluated the effect of FIT-039 on host cellular transcriptome, compared with Flavopiridol which is an existing pan-specific CDK9 inhibitor. HeLa cells were incubated with FIT-039 or flavopiridol at the concentration of IC80 for 24 hr, and cellular RNAs were collected and subjected to microarray analysis. The solvent DMSO was used as a negative control.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-57429http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-57429/samples/