{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "human", "factors": [{"GSM1382432": {"COMPOUND": "vehicle"}}, {"GSM138243": {"COMPOUND": "Flavopiridol"}}, {"GSM1382430": {"COMPOUND": "FIT-039"}}], "id": 2710, "ownerprofile_id": "arrayexpress_sid", "platform": 4, "summary_wrapped": "FIT-039 is a novel antiviral compound. Antiviral mechanism of FIT-039 is the inhibition of the viral transcription through suppression of...", "geo_gse_id": "E-GEOD-57429", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 1, "sample_count": 3, "tags": [], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "expression-data-from-fit-039-or-flavopiridol-compo", "geo_id_plat": "E-GEOD-57429_A-AFFY-44", "name": "Expression data from FIT-039 or Flavopiridol compound treated HeLa cells", "created": "Jul.22, 2014", "summary": "FIT-039 is a novel antiviral compound. Antiviral mechanism of FIT-039 is the inhibition of the viral transcription through suppression of the CTD phosphorylation of RNA polymerase II. We used microarrays to evaluated the effect of FIT-039 on host cellular transcriptome, compared with Flavopiridol which is an existing pan-specific CDK9 inhibitor. HeLa cells were incubated with FIT-039 or flavopiridol at the concentration of IC80 for 24 hr, and cellular RNAs were collected and subjected to microarray analysis. The solvent DMSO was used as a negative control.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-57429", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-57429/samples/"}