ArrayExpress Uploader0humanwithout poly I:CNeat1v2 vector transfectionwithout poly I:Cmock vector transfectionpoly I:C stimulationsiNEAT1 knockdown (siNEAT1 transfection)without poly I:CsiNEAT1 knockdown (siNEAT1 transfection)poly I:C stimulationcontrol (siCTRL transfection)without poly I:Ccontrol (siCTRL transfection)2042arrayexpress_sid4Although thousands of long non-coding RNAs (lncRNAs) are localized in the nucleus, only a few dozen have been functionally characterized....E-GEOD-56936/profile/8773/arrayexpressuploader26bodynuclear bodyDec.12, 2014Falseexpression-data-from-neat1-regulated-genes-with-orE-GEOD-56936_A-AFFY-44Expression data from NEAT1 regulated genes with or without polyI:CJul.10, 2014Although thousands of long non-coding RNAs (lncRNAs) are localized in the nucleus, only a few dozen have been functionally characterized. We found that nuclear paraspeckle assembly transcript 1 (NEAT1), an essential lncRNA for the formation of nuclear body paraspeckles, is induced by poly I:C stimulation, resulting in excess formation of paraspeckles. Using microarray analysis, we investigated whether NEAT1 induction followed by excess formation of paraspeckles was involved in poly I:C-inducible gene expression. We want to know the NEAT1-regulated genes. To the end, HeLa TO cells with and without poly I:C stimulation and NEAT1-knock down cells with and without poly I:C stimulation and cells transfected with mock plasmid or Neat1v2 expression plasmid alone were used for RNA extraction and hybridization on Affymetrix microarrays.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-56936http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-56936/samples/