{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "human", "factors": [{"GSM1371879": {"PROTOCOL": "without poly I:C", "GENOTYPE": "Neat1v2 vector transfection"}}, {"GSM1371878": {"PROTOCOL": "without poly I:C", "GENOTYPE": "mock vector transfection"}}, {"GSM1371877": {"PROTOCOL": "poly I:C stimulation", "GENOTYPE": "siNEAT1 knockdown (siNEAT1 transfection)"}}, {"GSM1371876": {"PROTOCOL": "without poly I:C", "GENOTYPE": "siNEAT1 knockdown (siNEAT1 transfection)"}}, {"GSM1371875": {"PROTOCOL": "poly I:C stimulation", "GENOTYPE": "control (siCTRL transfection)"}}, {"GSM1371874": {"PROTOCOL": "without poly I:C", "GENOTYPE": "control (siCTRL transfection)"}}], "id": 2042, "ownerprofile_id": "arrayexpress_sid", "platform": 4, "summary_wrapped": "Although thousands of long non-coding RNAs (lncRNAs) are localized in the nucleus, only a few dozen have been functionally characterized....", "geo_gse_id": "E-GEOD-56936", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 2, "sample_count": 6, "tags": ["body", "nuclear body"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "expression-data-from-neat1-regulated-genes-with-or", "geo_id_plat": "E-GEOD-56936_A-AFFY-44", "name": "Expression data from NEAT1 regulated genes with or without polyI:C", "created": "Jul.10, 2014", "summary": "Although thousands of long non-coding RNAs (lncRNAs) are localized in the nucleus, only a few dozen have been functionally characterized. We found that nuclear paraspeckle assembly transcript 1 (NEAT1), an essential lncRNA for the formation of nuclear body paraspeckles, is induced by poly I:C stimulation, resulting in excess formation of paraspeckles. Using microarray analysis, we investigated whether NEAT1 induction followed by excess formation of paraspeckles was involved in poly I:C-inducible gene expression. We want to know the NEAT1-regulated genes. To the end, HeLa TO cells with and without poly I:C stimulation and NEAT1-knock down cells with and without poly I:C stimulation and cells transfected with mock plasmid or Neat1v2 expression plasmid alone  were used for RNA extraction and hybridization on Affymetrix microarrays.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-56936", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-56936/samples/"}