Dataset: Inhibition of BET bromodomain proteins as a therapeutic approach in prostate cancer
We analyzed transcriptional changes in 4 prostate cancer cell lines following treatment with the BET inhibitor I-BET762 using Affymetrix...
We analyzed transcriptional changes in 4 prostate cancer cell lines following treatment with the BET inhibitor I-BET762 using Affymetrix Human Genome U133 Plus 2.0 Arrays. Four prostate cancer cell lines (NCI-H660, VCaP, LNCaP, PC-3) were treated with DMSO (control) or I-BET762 at 0.5uM or 10uM concentrations for 24 hours. Two biological replicates are included for each treatment group.
- Species:
- human
- Samples:
- 24
- Source:
- E-GEOD-56352
- PubMed:
- 24293458
- Updated:
- Dec.12, 2014
- Registered:
- Jul.11, 2014
Factors:
(via ArrayExpress)
Sample | CELL LINE | DOSE |
---|---|---|
GSM1359783 | Human cancer cell line, PC3 | 10uM |
GSM1359783 | Human cancer cell line, PC3 | 10uM |
GSM135978 | Human cancer cell line, PC3 | .5uM |
GSM135978 | Human cancer cell line, PC3 | .5uM |
GSM1359779 | Human cancer cell line, PC3 | vehicle |
GSM1359779 | Human cancer cell line, PC3 | vehicle |
GSM1359777 | Human cancer cell line, LNCAP | 10uM |
GSM1359777 | Human cancer cell line, LNCAP | 10uM |
GSM1359775 | Human cancer cell line, LNCAP | .5uM |
GSM1359775 | Human cancer cell line, LNCAP | .5uM |
GSM1359773 | Human cancer cell line, LNCAP | vehicle |
GSM1359773 | Human cancer cell line, LNCAP | vehicle |
GSM135977 | Human cancer cell line, VCAP | 10uM |
GSM135977 | Human cancer cell line, VCAP | 10uM |
GSM1359769 | Human cancer cell line, VCAP | .5uM |
GSM1359769 | Human cancer cell line, VCAP | .5uM |
GSM1359767 | Human cancer cell line, VCAP | vehicle |
GSM1359767 | Human cancer cell line, VCAP | vehicle |
GSM1359765 | Human cancer cell line, NCIH660 | 10uM |
GSM1359765 | Human cancer cell line, NCIH660 | 10uM |
GSM1359763 | Human cancer cell line, NCIH660 | .5uM |
GSM1359763 | Human cancer cell line, NCIH660 | .5uM |
GSM135976 | Human cancer cell line, NCIH660 | vehicle |
GSM135976 | Human cancer cell line, NCIH660 | vehicle |