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<biogps><data><item key="owner">ArrayExpress Uploader</item><item key="ownerprofile_id">arrayexpress_sid</item><item key="id">2024</item><item key="factors"><item><item key="GSM135798"><item key="CELL LINE">PC3 cells (obtained from ATCC)</item><item key="COMPOUND">LPA</item></item></item><item><item key="GSM135798"><item key="CELL LINE">PC3 cells (obtained from ATCC)</item><item key="COMPOUND">LPA</item></item></item><item><item key="GSM1357979"><item key="CELL LINE">PC3 cells (obtained from ATCC)</item><item key="COMPOUND">control</item></item></item><item><item key="GSM1357979"><item key="CELL LINE">PC3 cells (obtained from ATCC)</item><item key="COMPOUND">control</item></item></item><item><item key="GSM1357977"><item key="CELL LINE">MCF7 cells (obtained from ATCC)</item><item key="COMPOUND">LPA</item></item></item><item><item key="GSM1357977"><item key="CELL LINE">MCF7 cells (obtained from ATCC)</item><item key="COMPOUND">LPA</item></item></item><item><item key="GSM1357975"><item key="CELL LINE">MCF7 cells (obtained from ATCC)</item><item key="COMPOUND">control</item></item></item><item><item key="GSM1357975"><item key="CELL LINE">MCF7 cells (obtained from ATCC)</item><item key="COMPOUND">control</item></item></item><item><item key="GSM1357973"><item key="CELL LINE">MDA-MB-231 cells (obtained from ATCC)</item><item key="COMPOUND">LPA</item></item></item><item><item key="GSM1357973"><item key="CELL LINE">MDA-MB-231 cells (obtained from ATCC)</item><item key="COMPOUND">LPA</item></item></item><item><item key="GSM135797"><item key="CELL LINE">MDA-MB-231 cells (obtained from ATCC)</item><item key="COMPOUND">control</item></item></item><item><item key="GSM135797"><item key="CELL LINE">MDA-MB-231 cells (obtained from ATCC)</item><item key="COMPOUND">control</item></item></item></item><item key="pop_total">0</item><item key="platform">4</item><item key="summary_wrapped">LPA is a natural bioactive lipid with growth factor-like functions due to activation of series of six G protein-coupled receptors...</item><item key="pubmed_id">24828490</item><item key="geo_gse_id">E-GEOD-56265</item><item key="owner_profile">/profile/8773/arrayexpressuploader</item><item key="factor_count">2</item><item key="sample_count">12</item><item key="tags"><item>cancer</item><item>cell</item><item>genome</item><item>lipid</item><item>protein</item><item>serum</item></item><item key="lastmodified">Dec.12, 2014</item><item key="is_default">False</item><item key="geo_gds_id"/><item key="slug">transcriptomic-analysis-of-human-breast-and-prosta</item><item key="geo_id_plat">E-GEOD-56265_A-AFFY-44</item><item key="name">Transcriptomic analysis of human breast and prostate cancer cell lines on lysophosphatidic acid (LPA) stimulation</item><item key="created">Jul.10, 2014</item><item key="summary">LPA is a natural bioactive lipid with growth factor-like functions due to activation of series of six G protein-coupled receptors (LPA1-6). In this study we determine the LPA induced early-gene expression profile in three unrelated human cancer cell lines (MDA-MB-231, MCF7, PC3) with an objective to identify potential biomarker/s specifically upregulated through the activation of LPA receptor type 1 (LPA1) MDA-MB-231, MCF7, PC3 cells were serum starved for 24h and then stimulated with LPA (1&#181;M) for 45min. The controls were the serum starved unstimulated cells. Two replicates for each sample were included in this study. Microarray analysis was performed using a high-density oligonucleotide array (GeneChip Human Genome U133 plus 2.0 array, Affymetrix)</item><item key="source">http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-56265</item><item key="species">human</item><item key="sample_source">http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-56265/samples/</item></data></biogps>
