ArrayExpress Uploader0humanNegativeNTNegativeNTNegativeNTPositiveNTPositiveNTPositiveNTPositive10 micromolar MT-DADMe-ImmA InhibitorPositive10 micromolar MT-DADMe-ImmA InhibitorPositive10 micromolar MT-DADMe-ImmA Inhibitor4740arrayexpress_sid4Methylthioadenosine Phosphorylase (MTAP) is a tumor suppressor gene that encodes an enzyme responsible for the catabolism of the...E-GEOD-56112/profile/8773/arrayexpressuploader29fibrosarcomaDec.12, 2014Falseexpression-array-analysis-of-mtap-in-ht080-cellsE-GEOD-56112_A-AFFY-44Expression Array analysis of MTAP in HT080 cellsSep.21, 2014Methylthioadenosine Phosphorylase (MTAP) is a tumor suppressor gene that encodes an enzyme responsible for the catabolism of the polyamine byproduct 5′deoxy-5′-methylthioadenosine (MTA). To elucidate the mechanism by which MTAP inhibits tumor formation, we have created isogenic MTAP+ and MTAP- HT1080 fibrosarcoma cells. In this experiment we have performed expression array analysis on MTAP-, MTAP+, and MTAP+ cells treated with the MTAP inhibitor MT-DADMe-ImmA. Three biological replicates of each sample were grown and analyzed. M- is MTAP-. M+ is MTAP+, and M+I is MTAP treated with inhibitor (48 hours).http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-56112http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-56112/samples/