{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "human", "factors": [{"GSM1356054": {"MTAP": "Negative", "TREATMENT": "NT"}}, {"GSM1356054": {"MTAP": "Negative", "TREATMENT": "NT"}}, {"GSM1356054": {"MTAP": "Negative", "TREATMENT": "NT"}}, {"GSM1356057": {"MTAP": "Positive", "TREATMENT": "NT"}}, {"GSM1356057": {"MTAP": "Positive", "TREATMENT": "NT"}}, {"GSM1356057": {"MTAP": "Positive", "TREATMENT": "NT"}}, {"GSM1356060": {"MTAP": "Positive", "TREATMENT": "10 micromolar MT-DADMe-ImmA Inhibitor"}}, {"GSM1356060": {"MTAP": "Positive", "TREATMENT": "10 micromolar MT-DADMe-ImmA Inhibitor"}}, {"GSM1356060": {"MTAP": "Positive", "TREATMENT": "10 micromolar MT-DADMe-ImmA Inhibitor"}}], "id": 4740, "ownerprofile_id": "arrayexpress_sid", "platform": 4, "summary_wrapped": "Methylthioadenosine Phosphorylase (MTAP) is a tumor suppressor gene that encodes an enzyme responsible for the catabolism of the...", "geo_gse_id": "E-GEOD-56112", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 2, "sample_count": 9, "tags": ["fibrosarcoma"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "expression-array-analysis-of-mtap-in-ht080-cells", "geo_id_plat": "E-GEOD-56112_A-AFFY-44", "name": "Expression Array analysis of MTAP in HT080 cells", "created": "Sep.21, 2014", "summary": "Methylthioadenosine Phosphorylase (MTAP) is a tumor suppressor gene that encodes an enzyme responsible for the catabolism of the polyamine byproduct 5\u2032deoxy-5\u2032-methylthioadenosine (MTA).  To elucidate the mechanism by which MTAP inhibits tumor formation, we have created isogenic MTAP+ and MTAP- HT1080 fibrosarcoma cells. In this experiment we have performed expression array analysis on MTAP-, MTAP+, and MTAP+ cells treated with the MTAP inhibitor MT-DADMe-ImmA. Three biological replicates of each sample were grown and analyzed.  M- is MTAP-. M+ is MTAP+, and M+I is MTAP treated with inhibitor (48 hours).", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-56112", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-56112/samples/"}