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Home › Dataset Library › Gene expression profile of TRAIL-sensitive and -resistant H460 cells

Dataset: Gene expression profile of TRAIL-sensitive and -resistant H460 cells

We generated H460 cells with acquired TRAIL resistance by exposing the parental sentisitve cells to subtoxic concentrations of TRAIL for...

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We generated H460 cells with acquired TRAIL resistance by exposing the parental sentisitve cells to subtoxic concentrations of TRAIL for 6 months. Then we compared the gene expression profile of the sensitive versus the resistant cells. We generated acquired TRAIL-resistant H460 cells from the sentisitve cells by treating subtoxic range of TRAIL for 6 month. And we tried to compare the expressional profile of the genes between two cell types to isolate genes regulating acquired TRAIL-resistance H460 cells were treated with subtoxic concentrations of TRAIL for 6 month. After confirmation of the resistance, the RNA was extracted and the gene expression profile was analyzed.

Species:
human

Samples:
8

Source:
E-GEOD-55859

Updated:
Dec.12, 2014

Registered:
Sep.21, 2014


Factors: (via ArrayExpress)
Sample GENOTYPE
GSM1347627 control
GSM1347627 control
GSM1347627 control
GSM1347627 control
GSM134763 acquired TRAIL-resistance
GSM134763 acquired TRAIL-resistance
GSM134763 acquired TRAIL-resistance
GSM134763 acquired TRAIL-resistance

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  • cell

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