BioGPS
  • Home
  • Help
  • Plugins
  • Datasets
  • Sign Up
  • Login
Examples: Gene Symbol(s), Gene Ontology, Splicing plugins, Melanoma datasets
advanced
Home › Dataset Library › Effect of co-culture with macrophages on two colon cancer cell lines.

Dataset: Effect of co-culture with macrophages on two colon cancer cell lines.

These data suggest that co-culture with macrophages increases expression of NDRG-1 in epithelial cell lines. The finding is confirmed in...

Registered by ArrayExpress Uploader
View Dataset

These data suggest that co-culture with macrophages increases expression of NDRG-1 in epithelial cell lines. The finding is confirmed in 1 mouse epithelial cell line, and in tissue derived from mice genetically and dietetically altered to increase macrophage infiltration of the small and large intestinal epithelium. NDRG1 is identified as a potential mediator of macrophage effects on tumorigenesis in the large and small intestine. Array data is part of a larger study involving the effects of Vitamin D, in concert with macrophages, on intestinal homeostasis and tumorigenesis, entitled Cell autonomous and non-autonomous interactions of a western-style diet and the vitamin D receptor in intestinal homeostasis and tumorigenesis Cells from human colon cancer cell lines were cultured either alone, with Vitamin D3, with THP1 macrophages, or with THP1 macrophages and Vitamin D3, in a system which allowed no physical contact but exchange of soluble factors between the cell types.

Species:
human

Samples:
10

Source:
E-GEOD-55810

Updated:
Dec.12, 2014

Registered:
Jul.11, 2014


Factors: (via ArrayExpress)
Sample CELL LINE CELL TYPE CULTURED WITH
GSM1346305 THP1 macropahges VitD3 for 24h
GSM1346304 THP1 macropahges none (cultured alone)
GSM1346303 Hke3 Colorectal carcinoma cells THP1 macrophages
GSM1346302 Hke3 Colorectal carcinoma cells THP1 macrophages and Vitamin D3
GSM134630 Hke3 Colorectal carcinoma cells VitD3 for 24h
GSM1346300 Hke3 Colorectal carcinoma cells none (cultured alone)
GSM1346299 HCT116 Colorectal carcinoma cells THP1 macrophages
GSM1346298 HCT116 Colorectal carcinoma cells THP1 macrophages and Vitamin D3
GSM1346297 HCT116 Colorectal carcinoma cells none (cultured alone)
GSM1346296 HCT116 Colorectal carcinoma cells VitD3 for 24h

Tags

  • cancer
  • cell
  • colon
  • colon cancer
  • epithelial cell
  • intestinal epithelium
  • intestine
  • line
  • macrophage
  • small intestine

Other Formats

JSON    XML
  • About
  • Blog
  • Help
  • FAQ
  • Downloads
  • API
  • iPhone App
  • Email updates
© 2022 The Scripps Research Institute. All rights reserved. (ver 94eefe6 )
  • Terms of Use