ArrayExpress Uploader0mousecultured aloneCT26mouse colon tumor epithelial cellscocultured with macrophage RAW264CT26mouse colon tumor epithelial cellscultured aloneRAW264mouse macrophage cellscocultured with CT26 cellsRAW264mouse macrophage cellscultured aloneCT26mouse colon tumor epithelial cellscocultured with macrophage RAW264CT26mouse colon tumor epithelial cellscultured aloneRAW264mouse macrophage cellscocultured with CT26 cellsRAW264mouse macrophage cells7593arrayexpress_sid6These data suggest that co-culture with macrophages increases expression of NDRG-1 in epithelial cell lines. The finding is confirmed in...E-GEOD-55809/profile/8773/arrayexpressuploader38cellepithelial cellintestinal epitheliumintestinelinemacrophagesmall intestineDec.12, 2014FalseE-GEOD-55809_A-AFFY-45cell-autonomous-and-non-autonomous-interactions-ofCell autonomous and non-autonomous interactions of a western-style diet and the vitamin D receptor in intestinal homeostasis and tumorigenesisNov.12, 2014These data suggest that co-culture with macrophages increases expression of NDRG-1 in epithelial cell lines. The finding is confirmed in 2 human epithelial cell lines, and in tissue derived from mice genetically and dietetically altered to increase macrophage infiltration of the small and large intestinal epithelium. NDRG1 is identified as a potential mediator of macrophage effects on tumorigenesis in the large and small intestine. Array data is part of a larger study involving the effects of Vitamin D, in concert with macrophages, on intestinal homeostasis and tumorigenesis. Cells from mouse epithelial cell line CT26 were cultured either alone, or with RAW macrophages in a system which allowed no physical contact but exchange of soluble factors between the cell types. The experiment was peformed twice.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-55809http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-55809/samples/