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Home › Dataset Library › Expression data from the transplanted mouse islets into hyperglycemic and normoglycemic mice at 6 hours post-transplantation

Dataset: Expression data from the transplanted mouse islets into hyperglycemic and normoglycemic mice at 6 hours post-transplantation

insulin treatment protects islets from the initial rapid loss that is usually observed after transplantation and positively affects the...

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insulin treatment protects islets from the initial rapid loss that is usually observed after transplantation and positively affects the outcome of islet transplantation in Akita mice. To study the molecular mechanism underlying the improved islet survival, expression profile analyses was performed to analyze the differences between the grafts transplanted into hyperglycemic and normoglycemic mice at 6 hours post-transplantation Cells were harvested at grafts for RNA extraction and hybridization on Affymetrix microarrays. We performed gene expression profiles of the transplanted mouse islets into hyperglycemic and normoglycemic mice at 6 hours post-transplantation

Species:
mouse

Samples:
2

Source:
E-GEOD-55764

Updated:
Dec.12, 2014

Registered:
Nov.12, 2014


Factors: (via ArrayExpress)
Sample RECIPIENT STRAIN RECIPIENT MOUSE STATUS
GSM134576 wild type C57BL/6 normoglycemic
GSM1345762 heterozygous Akita hyperglycemic

Tags

  • insulin

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