ArrayExpress Uploader0humanweek 2, after ixekizumab 150mg subcutaneous treatment1803psoriasis patientsPsoriasis treatmentweek 2, after ixekizumab 150mg subcutaneous treatment1710psoriasis patientsPsoriasis treatmentweek 2, after ixekizumab 150mg subcutaneous treatment1615psoriasis patientsPsoriasis treatmentweek 2, after ixekizumab 150mg subcutaneous treatment1611psoriasis patientsPsoriasis treatmentweek 2, after ixekizumab 150mg subcutaneous treatment1209psoriasis patientsPsoriasis treatmentweek 2, after ixekizumab 150mg subcutaneous treatment1208psoriasis patientsPsoriasis treatmentweek 2, after ixekizumab 150mg subcutaneous treatment1207psoriasis patientsPsoriasis treatmentbaseline; before treatment1803psoriasis patientsPsoriasis Baselinebaseline; before treatment1710psoriasis patientsPsoriasis Baselinebaseline; before treatment1615psoriasis patientsPsoriasis Baselinebaseline; before treatment1611psoriasis patientsPsoriasis Baselinebaseline; before treatment1610psoriasis patientsPsoriasis Baselinebaseline; before treatment1209psoriasis patientsPsoriasis Baselinebaseline; before treatment1208psoriasis patientsPsoriasis Baselinebaseline; before treatment1207psoriasis patientsPsoriasis Baselinebaseline; before treatment1902psoriasis patientsPsoriasis Baselinebaseline; before treatment1707psoriasis patientsPsoriasis Baselinebaseline; before treatment1706psoriasis patientsPsoriasis Baselinebaseline; before treatment1612psoriasis patientsPsoriasis Baselinebaseline; before treatment1609psoriasis patientsPsoriasis Baselinebaseline; before treatment1608psoriasis patientsPsoriasis Baselinebaseline; before treatment1607psoriasis patientsPsoriasis Baselinebaseline; before treatment1109psoriasis patientsPsoriasis Baselinebaseline; before treatment1801psoriasis patientsPsoriasis Baselinebaseline; before treatment1606psoriasis patientsPsoriasis Baselinebaseline; before treatment1505psoriasis patientsPsoriasis Baselinebaseline; before treatment1410psoriasis patientsPsoriasis Baselinebaseline; before treatment1404psoriasis patientsPsoriasis Baselinebaseline; before treatment1403psoriasis patientsPsoriasis Baselinebaseline; before treatment1402psoriasis patientsPsoriasis Baselinebaseline; before treatment1401psoriasis patientsPsoriasis Baselinebaseline; before treatment1605psoriasis patientsPsoriasis Baselinebaseline; before treatment1504psoriasis patientsPsoriasis Baselinebaseline; before treatment1502psoriasis patientsPsoriasis Baselinebaseline; before treatment1303psoriasis patientsPsoriasis Baselinebaseline; before treatment1301psoriasis patientsPsoriasis Baselinebaseline; before treatment1104psoriasis patientsPsoriasis Baselinebaseline; before treatment1102psoriasis patientsPsoriasis Baselinebaseline; before treatment1604psoriasis patientsPsoriasis Baselinebaseline; before treatment1603psoriasis patientsPsoriasis Baselinebaseline; before treatment1602psoriasis patientsPsoriasis Baselinebaseline; before treatment1601psoriasis patientsPsoriasis Baselinebaseline; before treatment1205psoriasis patientsPsoriasis Baselinebaseline; before treatment1702psoriasis patientsPsoriasis Baselinebaseline; before treatment1614psoriasis patientsPsoriasis Baselinebaseline; before treatment1613psoriasis patientsPsoriasis Baselinebaseline; before treatment1507psoriasis patientsPsoriasis Baselinebaseline; before treatment1503psoriasis patientsPsoriasis Baselinebaseline; before treatment1405psoriasis patientsPsoriasis Baselinebaseline; before treatment1304psoriasis patientsPsoriasis Baselinebaseline; before treatment1108psoriasis patientsPsoriasis Baselinenot specified11855healthy volunteerHealthy Controlnot specified11854healthy volunteerHealthy Controlnot specified11853healthy volunteerHealthy Controlnot specified11852healthy volunteerHealthy Controlnot specified11851healthy volunteerHealthy Controlnot specified11850healthy volunteerHealthy Controlnot specified11849healthy volunteerHealthy Controlnot specified11848healthy volunteerHealthy Controlnot specified11847healthy volunteerHealthy Controlnot specified11846healthy volunteerHealthy Controlnot specified11824healthy volunteerHealthy Controlnot specified11823healthy volunteerHealthy Controlnot specified11822healthy volunteerHealthy Controlnot specified11821healthy volunteerHealthy Controlnot specified11820healthy volunteerHealthy Controlnot specified11819healthy volunteerHealthy Controlnot specified11818healthy volunteerHealthy Controlnot specified11817healthy volunteerHealthy Controlnot specified11816healthy volunteerHealthy Controlnot specified11815healthy volunteerHealthy Controlnot specified11699healthy volunteerHealthy Controlnot specified11698healthy volunteerHealthy Controlnot specified11697healthy volunteerHealthy Controlnot specified11696healthy volunteerHealthy Controlnot specified11695healthy volunteerHealthy Controlnot specified11694healthy volunteerHealthy Controlnot specified11693healthy volunteerHealthy Controlnot specified11692healthy volunteerHealthy Controlnot specified11691healthy volunteerHealthy Controlnot specified11690healthy volunteerHealthy Control2081arrayexpress_sid4The effect of anti-IL-17 treatment on systemic inflammation is not fully understand. Using cDNA microarray, genomic analysis methods such...E-GEOD-55201/profile/8773/arrayexpressuploader481psoriasisDec.12, 2014Falsesuppression-of-inflammation-in-psoriasis-blood-aftE-GEOD-55201_A-AFFY-44Suppression of inflammation in psoriasis blood after IL-17 treatment with ixekizumabJul.11, 2014The effect of anti-IL-17 treatment on systemic inflammation is not fully understand. Using cDNA microarray, genomic analysis methods such as GSEA and ingenuity, we characterized the transcriptional changes in the blood of psoriasis patients afer systemic neutralization of IL-17 compared to baseline (before treatment). We also compared the whole blood-derived transcriptome between psoraisis patients at baseline and healthy volunteers to examine systemic inflammation in psoriasis patients. total RNA was extratced from whole blood from psoriasis patients at baseline and after two weeks of treatment; total RNA was extracted from the whole blood of healthy individualshttp://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-55201http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-55201/samples/