ArrayExpress Uploader0mouseNxnl1-/-50 luxNxnl1+/+50 luxNxnl1-/-50 luxNxnl1+/+50 luxNxnl1-/-50 luxNxnl1-/-5000 luxNxnl1+/+2500 luxNxnl1+/+5000 luxNxnl1+/+2500 luxNxnl1+/+2500 luxNxnl1-/-5000 luxNxnl1+/+5000 luxNxnl1+/+5000 luxNxnl1-/-2500 luxNxnl1-/-2500 luxNxnl1-/-2500 lux7565arrayexpress_sid6Rod-derived Cone Viability Factor is a trophic factor of the thioredoxins family that promotes the survival of cone photoreceptors. It is...E-GEOD-54886/profile/8773/arrayexpressuploader216coneproteinDec.12, 2014FalseE-GEOD-54886_A-AFFY-45susceptibility-to-photo-oxidative-damage-of-mice-lSusceptibility to photo-oxidative damage of mice lacking the Rod derived Cone Viability Factor gene Nxnl1Nov.12, 2014Rod-derived Cone Viability Factor is a trophic factor of the thioredoxins family that promotes the survival of cone photoreceptors. It is encoded by the nucleoredoxin-like gene 1 Nxnl1 which also encodes by alternative splicing for RdCVFL, for a thioredoxin enzyme that interacts with the protein TAU. The role of thioredoxins in the defense mechanism against oxidation led us to examine the retinal phenotype of the Nxnl1-/- mouse after photo-oxidative stress. In total 16 samples were analyzed, they represent two different genotypes (wt/wt, ko/ko) both on pure BALB/c background and two doses of light that were tested in triplicate each.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-54886http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-54886/samples/