{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "mouse", "factors": [{"GSM1316745": {"CELL TYPE": "Encephalitogenic Tcells", "SURFACE MARKERS": "CD4+"}}, {"GSM1316745": {"CELL TYPE": "Encephalitogenic Tcells", "SURFACE MARKERS": "CD4+"}}, {"GSM1316745": {"CELL TYPE": "Encephalitogenic Tcells", "SURFACE MARKERS": "CD4+"}}, {"GSM1316748": {"CELL TYPE": "natural FoxA1Treg", "SURFACE MARKERS": "CD4hi,PD-L1hi"}}, {"GSM1316748": {"CELL TYPE": "natural FoxA1Treg", "SURFACE MARKERS": "CD4hi,PD-L1hi"}}, {"GSM1316748": {"CELL TYPE": "natural FoxA1Treg", "SURFACE MARKERS": "CD4hi,PD-L1hi"}}, {"GSM131675": {"CELL TYPE": "Treg", "SURFACE MARKERS": "CD4+,TGFbeta+"}}, {"GSM131675": {"CELL TYPE": "Treg", "SURFACE MARKERS": "CD4+,TGFbeta+"}}, {"GSM131675": {"CELL TYPE": "Treg", "SURFACE MARKERS": "CD4+,TGFbeta+"}}, {"GSM1316754": {"CELL TYPE": "induced FoxA1Treg", "SURFACE MARKERS": "CD4hi,PD-L1hi"}}, {"GSM1316754": {"CELL TYPE": "induced FoxA1Treg", "SURFACE MARKERS": "CD4hi,PD-L1hi"}}, {"GSM1316754": {"CELL TYPE": "induced FoxA1Treg", "SURFACE MARKERS": "CD4hi,PD-L1hi"}}], "id": 7554, "ownerprofile_id": "arrayexpress_sid", "platform": 6, "summary_wrapped": "Affymetrix gene expression analysis was carried out to investigate the differences in gene profile of MBP89-101-reactive encephalitogenic...", "geo_gse_id": "E-GEOD-54490", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 2, "sample_count": 12, "tags": ["cell", "membrane", "surface"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "foxa1-directs-the-lineage-and-immunosuppressive-pr", "geo_id_plat": "E-GEOD-54490_A-AFFY-45", "name": "FoxA1 directs the lineage and immunosuppressive properties of FoxA1+ regulatory T cells in EAE and MS", "created": "Nov.12, 2014", "summary": "Affymetrix gene expression analysis was carried out to investigate the differences in gene profile of MBP89-101-reactive encephalitogenic T cells before and after co-culture with cerebellar granular neurons (CGNs). Co-culture of MBP89-101-reactive encephalitogenic T cells with CGNs leads to generation of T cells with regulatory T cells phenotype (CD4+CD25+membrane bound TGF-b+ T cells) or a new regulatory phenotype (CD4highPD-L1high T cells). CGN-induced CD4+CD25+membrane bound TGF-b+ T regulatory cells, CD4highPD-L1high T cells were purified by FACSAria. IFN-beta induced T lymphocytes (CD4highPD-L1high T cells) were also FACSAria purified. All these populations were compared to  MBP89-101-reactive encephalitogenic T cells. Samples were prepared from biological triplicates for each FACSAria sorted population. There are four different cell types, as determined by cell surface markers, in triplicate in the experiment.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-54490", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-54490/samples/"}