{"owner": "ArrayExpress Uploader", "ownerprofile_id": "arrayexpress_sid", "species": "mouse", "factors": [{"GSM1306810": {"GENOTYPE": "E-FABP knockout"}}, {"GSM1306810": {"GENOTYPE": "E-FABP knockout"}}, {"GSM1306810": {"GENOTYPE": "E-FABP knockout"}}, {"GSM1306813": {"GENOTYPE": "wild type"}}, {"GSM1306813": {"GENOTYPE": "wild type"}}, {"GSM1306813": {"GENOTYPE": "wild type"}}], "id": 7542, "pop_total": 0, "platform": 6, "summary_wrapped": "E-FABP is dominately expressed in macrophages/dendritic cells. Thus E-FABP may play a siginificant role in their immune response to tumor...", "pubmed_id": 24713431, "geo_gse_id": "E-GEOD-54073", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 1, "sample_count": 6, "tags": ["bone", "bone marrow", "breast", "breast cancer", "cancer", "dendritic"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_id_plat": "E-GEOD-54073_A-AFFY-45", "slug": "gene-expression-microarray-data-of-bone-marrow-der", "geo_gds_id": "", "name": "Gene expression microarray data of bone marrow derived macrophages using GM-CSF(GM-BMMs) co-cultured with E0771 breast tumor cells", "created": "Nov.12, 2014", "summary": "E-FABP is dominately expressed in macrophages/dendritic cells. Thus E-FABP may play a siginificant role in their immune response to tumor insult. We treated mouse GM-BMMs of different genotype with E0771 breast cancer cells. Then we investigate the global gene expression in these GM-BMMs in response to tumor treatment. Bone marrow cells were collected from na\u00efve C57BL/6 and E-FABP knockout mice of 6~8 week old. GM-BMMs were derived using GM-CSF (in RPMI1640 with 5%FBS) for 7 days before tumor treatment. After 18hr tumor teatment, GM-BMM total RNA was extracted using RNeasy Mini Kit (Qiagen) and subjected to mouse mRNA Gene expression by Affymetrix microarray.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-54073", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-54073/samples/"}