ArrayExpress Uploader0humanCD40-activatedBC4885RestingBC4885CD40-activatedBC4884RestingBC4884CD40-activatedBC4870RestingBC4870CD40-activatedBC4869RestingBC48691204arrayexpress_sid3Antibody-independent effector functions of B cells, such as antigen presentation and cytokine production, have been shown to play an...E-GEOD-54017/profile/8773/arrayexpressuploader28cellcytokinediseaseDec.12, 2014Falsecd40-activation-of-human-b-cellsE-GEOD-54017_A-AFFY-33CD40-activation of human B cellsJun.18, 2014Antibody-independent effector functions of B cells, such as antigen presentation and cytokine production, have been shown to play an important role in a variety of immune-mediated conditions such as autoimmune diseases, transplant rejection and graft-versus-host disease. Therapeutic strategies, which interfere with B cell activation could therefore be a useful addition to the current immunosuppressive armamentarium. CD40 is one of the strongest activation stimuli for B cells. The aim of this study was to characterise the gene expression changes that occurr after B cell activation via CD40. Purified B cells isolated from PBMCs from four donors were compared to B cells whichhttp://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-54017http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-54017/samples/