ArrayExpress Uploaderarrayexpress_sid1846bipolar disorderbipolar disorderbipolar disordernormalnormalbipolar disorderbipolar disordernormalnormalbipolar disordernormalbipolar disordernormalbipolar disorderbipolar disordernormalbipolar disordernormalnormalbipolar disorderbipolar disordernormalnormalbipolar disordernormalnormalnormalbipolar disordernormalbipolar disorderbipolar disorderbipolar disordernormalnormalbipolar disordernormalbipolar disorderbipolar disorderbipolar disordernormalnormalnormalnormalbipolar disorderbipolar disordernormalbipolar disordernormalbipolar disorderbipolar disordernormalbipolar disordernormalnormalnormalbipolar disordernormalbipolar disorderbipolar disordernormalnormal03Bipolar affective disorder is a severe psychiatric disorder with a strong genetic component but unknown pathophysiology. We used...16894394E-GEOD-5388/profile/8773/arrayexpressuploader161bipolar disorderbraincortexdiseaseprefrontal cortexDec.12, 2014FalseE-GEOD-5388_A-AFFY-33transcription-profiling-of-human-brain-tissue-fromTranscription profiling of human brain tissue from subjects with bipolar disorder and healthy controlsJun.20, 2014Bipolar affective disorder is a severe psychiatric disorder with a strong genetic component but unknown pathophysiology. We used microarray technology (Affymetrix HG-U133A GeneChips) to determine the expression of approximately 22 000 mRNA transcripts in post-mortem brain tissue (dorsolateral prefrontal cortex) from patients with bipolar disorder and matched healthy controls. A cohort of 70 subjects was investigated and the final analysis included 30 bipolar and 31 control subjects. Differences between disease and control groups were identified using a rigorous statistical analysis with correction for confounding variables and multiple testing.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-5388humanhttp://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-5388/samples/