Dataset: Gene expression profiles in the liver of AIM+/+ and AIM-/- mice fed a high-fat diet

Expression of genes related to fibrosis was assessed in the liver of AIM+/+ and AM-/- mice fed a high-fat diet (HFD) for various period....

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Expression of genes related to fibrosis was assessed in the liver of AIM+/+ and AM-/- mice fed a high-fat diet (HFD) for various period. Overall, there was no significant difference in the magnitude of expression of fibrosis-related genes during the steatosis progression. AIM+/+ and AIM-/- mice were fed an HFD for 0, 12 or 20 weeks. Liver samples were homogenized with Trizol, and total RNA was extracted according to the manufacturer's instructions. Microarray experiments were performed using Mouse Genome 430 2.0 Arrays (Affymetrix).

Species:: mouse
Samples:: 18
Source:: E-GEOD-53834
Updated:: Dec.12, 2014
Registered:: Nov.12, 2014

Factors: (via ArrayExpress)

Sample	GENOTYPE	DIET
GSM1301768	wild type; AIM+/+	normal chow
GSM1301768	wild type; AIM+/+	normal chow
GSM1301768	wild type; AIM+/+	normal chow
GSM130177	AIM-KO; AIM-/-	normal chow
GSM130177	AIM-KO; AIM-/-	normal chow
GSM130177	AIM-KO; AIM-/-	normal chow
GSM1301774	wild type; AIM+/+	high-fat diet (HFD) for 12 weeks
GSM1301774	wild type; AIM+/+	high-fat diet (HFD) for 12 weeks
GSM1301774	wild type; AIM+/+	high-fat diet (HFD) for 12 weeks
GSM1301777	AIM-KO; AIM-/-	high-fat diet (HFD) for 12 weeks
GSM1301777	AIM-KO; AIM-/-	high-fat diet (HFD) for 12 weeks
GSM1301777	AIM-KO; AIM-/-	high-fat diet (HFD) for 12 weeks
GSM1301780	wild type; AIM+/+	high-fat diet (HFD) for 20 weeks
GSM1301780	wild type; AIM+/+	high-fat diet (HFD) for 20 weeks
GSM1301780	wild type; AIM+/+	high-fat diet (HFD) for 20 weeks
GSM1301783	AIM-KO; AIM-/-	high-fat diet (HFD) for 20 weeks
GSM1301783	AIM-KO; AIM-/-	high-fat diet (HFD) for 20 weeks
GSM1301783	AIM-KO; AIM-/-	high-fat diet (HFD) for 20 weeks