Dataset: Platelet-derived growth factor alpha mediates the proliferation of peripheral T-cell lymphoma cells via an autocrine regulatory pathway
Identification of the determinants of PDGFRA activity in PTCL/NOS (Peripheral T-cell lymphoma/not otherwise specified) and to elucidate...
Identification of the determinants of PDGFRA activity in PTCL/NOS (Peripheral T-cell lymphoma/not otherwise specified) and to elucidate the biological consequences of its activation. We generated GEP from samples of primary PTCL/NOS cells treated or not with imatinib mesylate (see below) as well as from EOL1 cells (3 samples each)
- Species:
- human
- Samples:
- 8
- Source:
- E-GEOD-53633
- Updated:
- Dec.12, 2014
- Registered:
- Jul.11, 2014
Factors:
(via ArrayExpress)
| Sample | TUMOR TYPE | CELL TYPE | TREATED WITH |
|---|---|---|---|
| GSM1297535 | Peripheral T-cell lymphoma/not otherwise specified (PTCL/NOS) | primary PTCL/NOS cells | none (control) |
| GSM1297535 | Peripheral T-cell lymphoma/not otherwise specified (PTCL/NOS) | primary PTCL/NOS cells | none (control) |
| GSM1297533 | Peripheral T-cell lymphoma/not otherwise specified (PTCL/NOS) | primary PTCL/NOS cells | 1 microM imatinib mesylate for 6 hrs |
| GSM1297533 | Peripheral T-cell lymphoma/not otherwise specified (PTCL/NOS) | primary PTCL/NOS cells | 1 microM imatinib mesylate for 6 hrs |
| GSM129753 | FIP1L1/PDGFRA+ hypereosinofilic leukemia | eosinophilic leukemia cells | none (control) |
| GSM129753 | FIP1L1/PDGFRA+ hypereosinofilic leukemia | eosinophilic leukemia cells | none (control) |
| GSM1297529 | FIP1L1/PDGFRA+ hypereosinofilic leukemia | eosinophilic leukemia cells | 1 microM imatinib mesylate for 6 hrs |
| GSM1297529 | FIP1L1/PDGFRA+ hypereosinofilic leukemia | eosinophilic leukemia cells | 1 microM imatinib mesylate for 6 hrs |