{"owner": "ArrayExpress Uploader", "pop_total": 0, "id": 4717, "factors": [{"GSM1279939": {"VECTOR TYPE": "ORF1"}}, {"GSM1279939": {"VECTOR TYPE": "ORF1"}}, {"GSM1279939": {"VECTOR TYPE": "ORF1"}}, {"GSM1279942": {"VECTOR TYPE": "Empty"}}, {"GSM1279942": {"VECTOR TYPE": "Empty"}}, {"GSM1279942": {"VECTOR TYPE": "Empty"}}], "ownerprofile_id": "arrayexpress_sid", "platform": 4, "summary_wrapped": "Adenovirus infection leads to increased glycolytic metabolism in host cells. Expression of a single gene product encoded within the E4...", "pubmed_id": 24703700, "geo_gse_id": "E-GEOD-52998", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 1, "sample_count": 6, "tags": ["glucose"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "adenovirus-promotes-host-cell-anabolic-glucose-met", "geo_id_plat": "E-GEOD-52998_A-AFFY-44", "name": "Adenovirus promotes host cell anabolic glucose metabolism via MYC activation", "created": "Sep.21, 2014", "summary": "Adenovirus infection leads to increased glycolytic metabolism in host cells. Expression of a single gene product encoded within the E4 early transcription region, E4ORF1, is sufficient to promote increased glycolytic flux in cultured epithelial cells. E4ORF1 reprograms cellular glucose metabolism by augmenting MYC-dependent transcription of metabolic genes. To gain insight into the mechanism by which E4ORF1 promotes increased glycolytic flux, we conducted a global microarray analysis of changes in RNA expression in MCF10A cells induced to accutely express ORF1 versus an empty vector.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-52998", "species": "human", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-52998/samples/"}