Dataset: Transcription profiling of whole lungs from mice expressing an inducible dominant negative BMPR2 transgene to study the effect of BMPR2 on gene expression.
Mice expressing a doxycycline-inducible dominant negative BMPR2 transgene expressed only in smooth muscle are activated for one or eight...
Mice expressing a doxycycline-inducible dominant negative BMPR2 transgene expressed only in smooth muscle are activated for one or eight weeks, and compared to transactivator-only mice also fed doxycycline. All mice are 12 weeks of old at sacrifice. Experiment Overall Design: Each chip is a pool of three individual mice, to reduce variability. The transactivator-only mice are controls. The other mice all had elevated RV pressures at time of sacrifice. RNA was prepared from whole lung.
- Species:
- mouse
- Samples:
- 6
- Source:
- E-GEOD-5255
- PubMed:
- 17369292
- Updated:
- Dec.12, 2014
- Registered:
- Nov.12, 2014
Factors:
(via ArrayExpress)
Sample | Time | Genotype | Sex |
---|---|---|---|
GSE5255GSM118653 | 8 | control | female |
GSE5255GSM118658 | 8 | control | male |
GSE5255GSM119284 | 1 | dominant-negative BMPR2 | female |
GSE5255GSM119286 | 8 | dominant-negative BMPR2 | female |
GSE5255GSM119285 | 1 | dominant-negative BMPR2 | male |
GSE5255GSM119287 | 8 | dominant-negative BMPR2 | male |