Dataset: Transcriptional responses of mantle cell lymphoma (MCL) lines to IKKB inhibition
MCL cell lines were treated with DMSO or 5uM AFN700 for 20hrs This experiment is designed to see if NFKB-target genes are downregulated...
MCL cell lines were treated with DMSO or 5uM AFN700 for 20hrs This experiment is designed to see if NFKB-target genes are downregulated by inhibition of IKKB in MCL cell lines that are insensitive to ibrutinib (BTK inhibitor) or sotrastaurin (PKC inhibitor) MCL cells were seeded in 6well dishes and treated for 20hrs with DMSO or 5uM AFN700
- Species:
- human
- Samples:
- 16
- Source:
- E-GEOD-52434
- Updated:
- Dec.12, 2014
- Registered:
- Jul.11, 2014
Factors:
(via ArrayExpress)
| Sample | STN/IBRUTINIB SENSITIVITY | CELL LINE | TREATMENT |
|---|---|---|---|
| GSM1266786 | insensitive | JVM-13 cells | 5uM AFN701 |
| GSM1266785 | insensitive | JVM-13 cells | 0.025% DMSO |
| GSM1266784 | insensitive | JVM-2 cells | 5uM AFN700 |
| GSM1266783 | insensitive | JVM-2 cells | 0.025% DMSO |
| GSM1266782 | insensitive | Maver-1 cells | 5uM AFN700 |
| GSM126678 | insensitive | Maver-1 cells | 0.025% DMSO |
| GSM1266780 | insensitive | Z-138 cells | 5uM AFN700 |
| GSM1266779 | insensitive | Z-138 cells | 0.025% DMSO |
| GSM1266778 | insensitive | GRANTA-519 cells | 5uM AFN700 |
| GSM1266777 | insensitive | GRANTA-519 cells | 0.025% DMSO |
| GSM1266776 | insensitive | HBL-2 cells | 5uM AFN700 |
| GSM1266775 | insensitive | HBL-2 cells | 0.025% DMSO |
| GSM1266774 | sensitive | SP49 cells | 5uM AFN700 |
| GSM1266773 | sensitive | SP49 cells | 0.025% DMSO |
| GSM1266772 | sensitive | REC-1 cells | 5uM AFN700 |
| GSM126677 | sensitive | REC-1 cells | 0.025% DMSO |