ArrayExpress Uploader0mouseTetO-NICD1 (control)48hTetO-NICD1 (control)48hTetO-NICD1 (control)48hTetO-NICD1 (control)48hTetO-NICD1 (control)96hTetO-NICD1 (control)96hTetO-NICD1 (control)96hMMTV-rtTA; TetO-NICD148hMMTV-rtTA; TetO-NICD148hMMTV-rtTA; TetO-NICD148hMMTV-rtTA; TetO-NICD148hMMTV-rtTA; TetO-NICD196hMMTV-rtTA; TetO-NICD196hMMTV-rtTA; TetO-NICD196hMMTV-rtTA; TetO-NICD196h7465arrayexpress_sid6Notch signaling is widely implicated in mouse mammary gland development and tumorigenesis. To investigate the effects of acute...E-GEOD-51628/profile/8773/arrayexpressuploader215compartmentglandnotchDec.12, 2014Falseeffects-of-acute-notch-activation-on-the-mammary-eE-GEOD-51628_A-AFFY-45Effects of acute Notch activation on the mammary epithelial compartment in vivoNov.12, 2014Notch signaling is widely implicated in mouse mammary gland development and tumorigenesis. To investigate the effects of acute activation of Notch signaling in the mammary epithelial compartment, we generated bi-transgenic MMTV-rtTA; TetO-NICD1 (MTB/TICNX) mice that conditionally express a constitutively active NOTCH1 intracellular domain (NICD1) construct in the mammary epithelium upon doxycycline administration. Two timepoints (48h and 96h) of doxycycline induction in TetO-NICD1 (TICNX; control) and MMTV-rtTA; TetO-NICD1 (MTB/TICNX) mice with 3-4 replicates per timepointhttp://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-51628http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-51628/samples/