{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "mouse", "factors": [{"GSM1249689": {"GENOTYPE": "TetO-NICD1 (control)", "TIME": "48h"}}, {"GSM1249689": {"GENOTYPE": "TetO-NICD1 (control)", "TIME": "48h"}}, {"GSM1249689": {"GENOTYPE": "TetO-NICD1 (control)", "TIME": "48h"}}, {"GSM1249689": {"GENOTYPE": "TetO-NICD1 (control)", "TIME": "48h"}}, {"GSM1249693": {"GENOTYPE": "TetO-NICD1 (control)", "TIME": "96h"}}, {"GSM1249693": {"GENOTYPE": "TetO-NICD1 (control)", "TIME": "96h"}}, {"GSM1249693": {"GENOTYPE": "TetO-NICD1 (control)", "TIME": "96h"}}, {"GSM1249696": {"GENOTYPE": "MMTV-rtTA; TetO-NICD1", "TIME": "48h"}}, {"GSM1249696": {"GENOTYPE": "MMTV-rtTA; TetO-NICD1", "TIME": "48h"}}, {"GSM1249696": {"GENOTYPE": "MMTV-rtTA; TetO-NICD1", "TIME": "48h"}}, {"GSM1249696": {"GENOTYPE": "MMTV-rtTA; TetO-NICD1", "TIME": "48h"}}, {"GSM1249700": {"GENOTYPE": "MMTV-rtTA; TetO-NICD1", "TIME": "96h"}}, {"GSM1249700": {"GENOTYPE": "MMTV-rtTA; TetO-NICD1", "TIME": "96h"}}, {"GSM1249700": {"GENOTYPE": "MMTV-rtTA; TetO-NICD1", "TIME": "96h"}}, {"GSM1249700": {"GENOTYPE": "MMTV-rtTA; TetO-NICD1", "TIME": "96h"}}], "id": 7465, "ownerprofile_id": "arrayexpress_sid", "platform": 6, "summary_wrapped": "Notch signaling is widely implicated in mouse mammary gland development and tumorigenesis.  To investigate the effects of acute...", "geo_gse_id": "E-GEOD-51628", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 2, "sample_count": 15, "tags": ["compartment", "gland", "notch"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "effects-of-acute-notch-activation-on-the-mammary-e", "geo_id_plat": "E-GEOD-51628_A-AFFY-45", "name": "Effects of acute Notch activation on the mammary epithelial compartment in vivo", "created": "Nov.12, 2014", "summary": "Notch signaling is widely implicated in mouse mammary gland development and tumorigenesis.  To investigate the effects of acute activation of Notch signaling in the mammary epithelial compartment, we generated bi-transgenic MMTV-rtTA; TetO-NICD1 (MTB/TICNX) mice that conditionally express a constitutively active NOTCH1 intracellular domain (NICD1) construct in the mammary epithelium upon doxycycline administration. Two timepoints (48h and 96h) of doxycycline induction in TetO-NICD1 (TICNX; control) and MMTV-rtTA; TetO-NICD1 (MTB/TICNX) mice with 3-4 replicates per timepoint", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-51628", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-51628/samples/"}