Dataset: Transcription profiling of human CD* T lymphocytes overexpressing hTERT

Using CD8+ T lymphocyte clones over-expressing telomerase weinvestigated the molecular mechanisms that regulate T cell proliferation. Transduction and subcloning procedures were performed on CD8 + naive T-cell clones isolated from two different healthy individuals aged between 30 to 35 years (HD1 and HD2). T-cell cloneswere transduced to express hTERT/GFP or GFP alone. HD1 was profiled on U133A and submitted as a separate GEO series. Experiment Overall Design: triplicates of 4 conditions, 1 condition (GFP YOUNG) lost because of problems in cell culture.

Species:

human

Samples:

9

Source:

E-GEOD-5143

PubMed:

16951325

Updated:

Dec.12, 2014

Registered:

Sep.21, 2014