{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "mouse", "factors": [{"GSM1240952": {"GENOTYPE": "ICN1", "ORGANISM PART": "bone marrow"}}, {"GSM1240952": {"GENOTYPE": "ICN1", "ORGANISM PART": "bone marrow"}}, {"GSM1240952": {"GENOTYPE": "ICN1", "ORGANISM PART": "bone marrow"}}, {"GSM1240955": {"GENOTYPE": "TEL-JAK2", "ORGANISM PART": "thymus"}}, {"GSM1240955": {"GENOTYPE": "TEL-JAK2", "ORGANISM PART": "thymus"}}, {"GSM1240955": {"GENOTYPE": "TEL-JAK2", "ORGANISM PART": "thymus"}}, {"GSM1240955": {"GENOTYPE": "TEL-JAK2", "ORGANISM PART": "thymus"}}], "id": 7449, "ownerprofile_id": "arrayexpress_sid", "platform": 6, "summary_wrapped": "The TEL-JAK2 fusion oncogene and the ICN1 activated allele of NOTCH1 are the result of specific chromosomal translocations in T cell...", "geo_gse_id": "E-GEOD-51243", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 2, "sample_count": 7, "tags": ["acute lymphoblastic leukemia", "bone", "bone marrow", "cell", "leukemia", "lymphoblastic leukemia", "thymus"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_id_plat": "E-GEOD-51243_A-AFFY-45", "slug": "comparison-of-the-transcriptome-of-tel-jak2-versus", "geo_gds_id": "", "name": "Comparison of the transcriptome of TEL-JAK2- versus activated NOTCH1 (ICN1)-induced T cell acute lymphoblastic leukemias (mouse)", "created": "Nov.12, 2014", "summary": "The TEL-JAK2 fusion oncogene and the ICN1 activated allele of NOTCH1 are the result of specific chromosomal translocations in T cell acute lymphoblastic leukemia (T-ALL). Mouse models of these diseases (TEL-JAK2 transgenic mice; Carron C.  et al. Blood (2000); a bone marrow transplantation model for ICN1-induced T-ALL) were used  to compare the transcriptional program specific to each oncoprotein in mouse models of these leukemias. Tumor load was >50% leukemic cells in all selected organs. Leukemic cells were collected from the thymus of terminally-ill TEL-JAK2 leukemic mice and bone marrow of terminally-ill ICN1 leukemic mice. RNA was extracted from each sample and processed for hybridization to Affymetrix arrays.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-51243", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-51243/samples/"}