ArrayExpress Uploader0humanpolysomal RNAUL38 inducedpolysomal RNAUL38 inducedpolysomal RNAuninducedpolysomal RNAuninducedextracted total RNAUL38 inducedextracted total RNAUL38 inducedextracted total RNAuninducedextracted total RNAuninducedpolysomal RNAHCMV infectedpolysomal RNAHCMV infectedpolysomal RNAMock infectedpolysomal RNAMock infectedextracted total RNAHCMV infectedextracted total RNAHCMV infectedextracted total RNAMock infectedextracted total RNAMock infected2239arrayexpress_sid4Genome-wide profiling establishes that human cytomegalovirus (HCMV) exerts an extensive, unforeseen level of specific control over which...E-GEOD-50938/profile/8773/arrayexpressuploader216cancercellgenomeDec.12, 2014Falseglobal-reprogramming-of-the-cellular-translationalE-GEOD-50938_A-AFFY-44Global reprogramming of the cellular translational landscape facilitates cytomegalovirus replicationJul.11, 2014Genome-wide profiling establishes that human cytomegalovirus (HCMV) exerts an extensive, unforeseen level of specific control over which cellular mRNAs are recruited to or excluded from polyribosomes. The landscape of translationally-regulated host mRNAs regulates HCMV replication. The HCMV imposed translational signature shares similarities with cancer cells Two biological replicate experiments were performed profiling total and polysomal mRNAs from i) HCMV-infected vs mock-infected cells and ii) uninfected cells transduced with a lentivirus expressing doxycyclin (dox)-inducible HCMV UL38 +/- dox. Analysis of translationally-controlled host genes in HCMV-infected cell and cells expressing the HCMV UL38 gene producthttp://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-50938http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-50938/samples/