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Home › Dataset Library › Transcription profiling of human thyroid cells exposed to INF-gamma and IL1-beta

Dataset: Transcription profiling of human thyroid cells exposed to INF-gamma and IL1-beta

Normal primary thyroid cells were incubated with , 100 IU/ml IFN-gamma, 50 IU/ml IL1-beta, or a combination of both IFN-gamma and...

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Normal primary thyroid cells were incubated with , 100 IU/ml IFN-gamma, 50 IU/ml IL1-beta, or a combination of both IFN-gamma and IL1-beta for 24 or 72 hours. The experiment was repeated 5 times using thyroid cells from 5 different patients. RNA expression was analyzed using Affymetrix HG_U133A arrays for 3 of the thyroids, and HG_U133A_2.0 (small version of HG_U133A) arrays for 2 of the thyroids. Experiment Overall Design: Normal primary thyroid cells were incubated with , 100 IU/ml IFN-gamma, 50 IU/ml IL1-beta, or a combination of both IFN-gamma and IL1-beta for 24 or 72 hours. The experiment was repeated 5 times using thyroid cells from 5 different patients. One array was hybridized per sample (20 samples). Experiment Overall Design: The probe-set intensities with accompanying statistical analysis (2-way ANOVA) and the associated README file are included as Supplementary files.

Species:
human

Samples:
12

Source:
E-GEOD-5054

PubMed:
17640998

Updated:
Jan.21, 2015

Registered:
Jan.21, 2015


Factors: (via ArrayExpress)
Sample INDIVIDUAL COMPOUND
GSE5054GSM113926 subject 1
GSE5054GSM113927 subject 1
GSE5054GSM113928 subject 1
GSE5054GSM113929 subject 1 IL1-beta
GSE5054GSM113930 subject 2
GSE5054GSM113931 subject 2
GSE5054GSM113932 subject 2
GSE5054GSM113933 subject 2 IL1-beta
GSE5054GSM113934 subject 3
GSE5054GSM113935 subject 3
GSE5054GSM113936 subject 3
GSE5054GSM113937 subject 3 IL1-beta

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