ArrayExpress Uploaderarrayexpress_sidhumanPPARβ/δ agonistnormoxiaPPARβ/δ agonisthypoxiaDMSOnormoxiaDMSOhypoxia210404Recently the role of PPARβ/δ in angiogenesis has been revealed, and we hypothesized that the crosstalk between hypoxia and PPARβ/δ on...E-GEOD-50378/profile/8773/arrayexpressuploader24Dec.12, 2014Falseexpression-data-of-huvec-cells-after-ppar-agonistE-GEOD-50378_A-AFFY-44Expression data of HUVEC cells after PPARβ/δ agonist and/or hypoxia treatmentJul.11, 2014Recently the role of PPARβ/δ in angiogenesis has been revealed, and we hypothesized that the crosstalk between hypoxia and PPARβ/δ on endothelial cells may exsist. To elucidate the interaction between two signalings, we report the comprehensive change of transcripts induced by PPARβ/δ agonist (GW501516) and/or hypoxia. We used microarray analysis of HUVECs treated with PPARβ/δ agonist (GW501516) and/or hypoxia (1% O2) for 24-hours, and we identified a group of consistently up- or down-regulated genes. HUVECs were used within the first 6 passages. HUVECs were treated with PPARβ/δ agonist (GW501516) at a concentration of 100 nM and/or hypoxia (1% O2) for 24-hours. Same concentration of DMSO was used as a control sample, and as to the oxgen, normoxia was used as a control condition.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-50378http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-50378/samples/