ArrayExpress Uploader07407Runx3 +/+IL-2Runx3 +/+IL-2Runx3 +/+IL-2Runx3 -/-IL-2Runx3 -/-IL-2Runx3 -/-IL-2Runx3 +/+IL-15Runx3 +/+IL-15Runx3 -/-IL-15Runx3 -/-IL-15arrayexpress_sid6NK cells are innate immune cells that recognize and kill foreign, virally-infected and tumor cells without the need for prior...24236182E-GEOD-50122/profile/8773/arrayexpressuploader210spleenviral infectionDec.12, 2014Falserunx3-function-in-splenic-nk-cells-il-2-or-il-15E-GEOD-50122_A-AFFY-45Runx3 function in splenic NK cells (IL-2 or IL-15)Nov.12, 2014NK cells are innate immune cells that recognize and kill foreign, virally-infected and tumor cells without the need for prior immunization. NK expansion following viral infection is IL-2 or IL-15-dependent. To identify Runx3 responsive genes, NK cells were isolated from spleen of WT and Runx3-/- mice . Ten samples (5 WT and 5 Runx3-/-) of freshly isolated NK cells were separately obtained from individual mice. Cells were cultured for 7 days with IL-2 or IL-15.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-50122mousehttp://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-50122/samples/