{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "mouse", "factors": [{"GSM1212750": {"GENOTYPE": "Wild type", "TREATMENT": "untreated"}}, {"GSM1212750": {"GENOTYPE": "Wild type", "TREATMENT": "untreated"}}, {"GSM1212750": {"GENOTYPE": "Wild type", "TREATMENT": "untreated"}}, {"GSM1212753": {"GENOTYPE": "Wild type", "TREATMENT": "RA-treated"}}, {"GSM1212753": {"GENOTYPE": "Wild type", "TREATMENT": "RA-treated"}}, {"GSM1212753": {"GENOTYPE": "Wild type", "TREATMENT": "RA-treated"}}, {"GSM1212756": {"GENOTYPE": "Hepatic RXR\u03b1-Knockout", "TREATMENT": "untreated"}}, {"GSM1212756": {"GENOTYPE": "Hepatic RXR\u03b1-Knockout", "TREATMENT": "untreated"}}, {"GSM1212756": {"GENOTYPE": "Hepatic RXR\u03b1-Knockout", "TREATMENT": "untreated"}}, {"GSM1212759": {"GENOTYPE": "Hepatic RXR\u03b1-Knockout", "TREATMENT": "RA-treated"}}, {"GSM1212759": {"GENOTYPE": "Hepatic RXR\u03b1-Knockout", "TREATMENT": "RA-treated"}}, {"GSM1212759": {"GENOTYPE": "Hepatic RXR\u03b1-Knockout", "TREATMENT": "RA-treated"}}], "id": 8725, "ownerprofile_id": "arrayexpress_sid", "platform": 8, "summary_wrapped": "Our project focuses on retinoic acid (RA) effect on hepatic lipid homeostasis. Even though RA has more than one receptor including...", "geo_gse_id": "E-GEOD-50028", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 2, "sample_count": 12, "tags": ["lipid", "liver"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "gene-expression-data-of-untreated-and-ra-treated-w", "geo_id_plat": "E-GEOD-50028_A-AFFY-36", "name": "Gene expression data of untreated and RA-treated wild type and RXR\u03b1-deficient mice liver", "created": "Nov.24, 2014", "summary": "Our project focuses on retinoic acid (RA) effect on hepatic lipid homeostasis. Even though RA has more than one receptor including retinoids x receptor (RXR) and retinoic acid receptor (RAR), most probably, RA effect on lipid homeostasis is mediated by RXR and its partners such as PXR, FXR, and PPAR. So we treated the wild type and RXR\u03b1-knockout mice by retinoic acid to check the global gene expression especially for lipid homeostasis genes. We used microarrays to observe the global gene expression underlying hepatic lipid homeostasis. We treated both the wild type and RXR\u03b1-KO mice with normal diet and RA-containing diet for 7 days. For each group, three replicates were done. Liver total RNA were used to test global gene expression by microarray.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-50028", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-50028/samples/"}