ArrayExpress Uploader0humanWTnot specifiednot specified12not specifiedmalefrontal lobenot specifiednot specifiedWTnot specifiednot specified5not specifiedfemaletemporal lobenot specifiednot specifiedK27Mnot specifiednot specified18not specifiedfemalethe fourth ventricle & brain stemnot specifiednot specifiedWTnot specifiednot specified14not specifiedfemaleparieto-occipitalnot specifiednot specifiedK27Mnot specifiednot specified24not specifiedmalethalamusnot specifiednot specifiedK27Mponsnot specifiednot specified6femalenot specifiedWTK27K27Mthalamicnot specifiednot specified7femalenot specifiedWTK27WTNAnot specifiednot specified38malenot specifiedWTMesenchymalK27Mthalamicnot specifiednot specified23femalenot specifiedWTK27WTNAnot specifiednot specified36malenot specifiedWTMesenchymalWTNAnot specifiednot specified34malenot specifiedMUTMesenchymalWTNAnot specifiednot specified46femalenot specifiedWTMesenchymalWTfrontal lobenot specifiednot specified13femalenot specifiedWTMesenchymalK27Mthalamicnot specifiednot specified11femalenot specifiedWTK27K27MVentricularnot specifiednot specified10femalenot specifiedWTK27not specifiednot specifiedK27M8not specifiedfemalenot specifiednot specifiednot specifiednot specifiednot specifiedK27M6not specifiedfemalenot specifiednot specifiednot specifiednot specifiednot specifiedK27M11not specifiedmalenot specifiednot specifiednot specifiednot specifiednot specifiedwt14not specifiedmalenot specifiednot specifiednot specifiednot specifiednot specifiedK27M10not specifiedmalenot specifiednot specifiednot specifiednot specifiednot specifiedwt14not specifiedmalenot specifiednot specifiednot specifiednot specifiednot specifiedK27M5not specifiedmalenot specifiednot specifiednot specified2035arrayexpress_sid4Pediatric high-grade gliomas (pHGGs) harboring the K27M mutation of H3F3A (histone H3.3) are characterized by global reduction of the...24183680/profile/8773/arrayexpressuploader922genomehistonehistone h3Dec.12, 2014FalseE-GEOD-49822_A-AFFY-44gene-expression-data-of-phgg-tumor-sampleshttp://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-49822Gene expression data of pHGG tumor samplesJul.10, 2014Pediatric high-grade gliomas (pHGGs) harboring the K27M mutation of H3F3A (histone H3.3) are characterized by global reduction of the repressive histone mark H3K27me3 and DNA hypomethylation. Analysis of K27M-induced changes on H3K27me3 occupancy and DNA methylation at differentially expresed genes (K27M vs. wild-type H3.3) in primary pHGG tumor samples. 22 glioblastoma samples from pHGG patients were selected for RNA extraction and hybridization on Affymetrix Affymetrix Human Genome U133 Plus 2.0 Arrays. Expression profiling data of 17 pHHGs are part of our previous study (GSE36245 or GSE34824).E-GEOD-49822http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-49822/samples/