ArrayExpress Uploader07385arrayexpress_sid6The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in MLL-AF9 AML. We evaluated the dependance on beta-...24189294E-GEOD-49248/profile/8773/arrayexpressuploader012bonebone marrowleukemiaDec.12, 2014Falsekrasg12d-partially-compensates-for-the-loss-of-betE-GEOD-49248_A-AFFY-45KrasG12D partially compensates for the loss of beta-catenin in MLL-AF9 AMLNov.12, 2014The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in MLL-AF9 AML. We evaluated the dependance on beta-catenin for KrasG12DMLL-AF9 leukemia. Lin-Kit+ bone marrow cells obtained from mice transplanted with primary MLL-AF9 leukemia cells and KRasG12DMLL-AF9 leukemia cells were assessed for gene expression in the presence or absence of beta-cateninhttp://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-49248mousehttp://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-49248/samples/