ArrayExpress Uploader0humanGAS2DNcontrol2346arrayexpress_sid4GAS2DN could suppress the growth of chronic myeloid leukemia cells, including K562, MEG-01 and CD34+ cells from patients. In addition,...E-GEOD-49184/profile/8773/arrayexpressuploader12chronic myeloid leukemialeukemiamyeloid leukemiaDec.12, 2014Falsethe-gene-expression-upon-dominant-negative-form-ofE-GEOD-49184_A-AFFY-44The gene expression upon dominant negative form of GAS2 (GAS2DN) in MEG-01 cellsJul.12, 2014GAS2DN could suppress the growth of chronic myeloid leukemia cells, including K562, MEG-01 and CD34+ cells from patients. In addition, GAS2DN inhibited the tumorigenic ability of MEG-01 cells in nude mice. To understand the molecular insight of this inhibitory effect of GAS2DN, global gene expression were performed. The control and GAS2DN-transduced MEG-01 cells were used for microarray analysis. Three biological independent extracts of control and GAS2DN-transduced cells were pooled together with equal amount, and then the pooled samples were compared with Affymetrix chips.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-49184http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-49184/samples/