{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "human", "factors": [{"GSM119516": {"TRANSDUCTION": "GAS2DN"}}, {"GSM1195160": {"TRANSDUCTION": "control"}}], "id": 2346, "ownerprofile_id": "arrayexpress_sid", "platform": 4, "summary_wrapped": "GAS2DN could suppress the growth of chronic myeloid leukemia cells, including K562, MEG-01 and CD34+ cells from patients. In addition,...", "geo_gse_id": "E-GEOD-49184", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 1, "sample_count": 2, "tags": ["chronic myeloid leukemia", "leukemia", "myeloid leukemia"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "the-gene-expression-upon-dominant-negative-form-of", "geo_id_plat": "E-GEOD-49184_A-AFFY-44", "name": "The gene expression upon dominant negative form of GAS2 (GAS2DN) in MEG-01 cells", "created": "Jul.12, 2014", "summary": "GAS2DN could suppress the growth of chronic myeloid leukemia cells, including K562, MEG-01 and CD34+ cells from patients. In addition, GAS2DN inhibited the tumorigenic ability of MEG-01 cells in nude mice. To understand the molecular insight of this inhibitory effect of GAS2DN, global gene expression were performed. The control and GAS2DN-transduced MEG-01 cells were used for microarray analysis. Three biological independent extracts of control and GAS2DN-transduced cells were pooled together with equal amount, and then the pooled samples were compared with Affymetrix chips.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-49184", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-49184/samples/"}