ArrayExpress Uploader07375C57BL/6Jisotonic saline1hC57BL/6Jisotonic saline1hC57BL/6Jisotonic saline1hC57BL/6Jkainic acid4hC57BL/6Jkainic acid4hC57BL/6Jkainic acid4hC57BL/6Jkainic acid8hC57BL/6Jkainic acid8hC57BL/6Jkainic acid8hC57BL/6Jkainic acid24hC57BL/6Jkainic acid24hC57BL/6Jkainic acid24hC57BL/6Jkainic acid1hC57BL/6Jkainic acid1hC57BL/6Jkainic acid1hC57BL/6Jisotonic saline1hC57BL/6Jisotonic saline1hC57BL/6Jisotonic saline1h129/Sv x C57Bl/6Jkainic acid4h129/Sv x C57Bl/6Jkainic acid4h129/Sv x C57Bl/6Jkainic acid4h129/Sv x C57Bl/6Jisotonic saline0h129/Sv x C57Bl/6Jisotonic saline0h129/Sv x C57Bl/6Jisotonic saline0harrayexpress_sid6Activity-dependent gene expression is central for sculpting neuronal connectivity in the brain. Despite the importance for synaptic...24146943E-GEOD-49030/profile/8773/arrayexpressuploader324braincentralgenomehippocampusDec.12, 2014Falsegenome-wide-profiling-of-the-activity-dependent-hiE-GEOD-49030_A-AFFY-45Genome-wide profiling of the activity-dependent hippocampal transcriptomeNov.12, 2014Activity-dependent gene expression is central for sculpting neuronal connectivity in the brain. Despite the importance for synaptic plasticity, a comprehensive analysis of the temporal changes in the transcriptomic response to neuronal activity is lacking. In a genome wide survey we identified genes that were induced at 1, 4, 8, or 24 hours following neuronal activity in the hippocampus. 3 month old male mice were injected with kainic acid or isotonic saline solution. Animals were sacrificed by cervical luxation 1, 2, 4, 8, or 24 h after onset of the first seizure, and RNA was extracted from the hippocampal region.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-49030mousehttp://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-49030/samples/