{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "human", "factors": [{"GSM1184608": {"CO-CULTURED WITH": "MDA-MB231 breast cancer cells"}}, {"GSM1184608": {"CO-CULTURED WITH": "MDA-MB231 breast cancer cells"}}, {"GSM1184608": {"CO-CULTURED WITH": "MDA-MB231 breast cancer cells"}}, {"GSM1184605": {"CO-CULTURED WITH": "none (control)"}}, {"GSM1184605": {"CO-CULTURED WITH": "none (control)"}}, {"GSM1184605": {"CO-CULTURED WITH": "none (control)"}}], "id": 2170, "ownerprofile_id": "arrayexpress_sid", "platform": 4, "summary_wrapped": "We studied the crosstalk between tumor and endothelial cells to explore the role of tumor microenvironment on cancer growth and...", "geo_gse_id": "E-GEOD-48786", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 1, "sample_count": 6, "tags": ["breast", "breast tumor", "cancer", "cytokine", "endothelium", "serum"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "expression-data-from-endothelial-cells-sorted-from", "geo_id_plat": "E-GEOD-48786_A-AFFY-44", "name": "Expression data from endothelial cells sorted from breast cancer cells MDA-MB231 as compared with normal endothelial cells", "created": "Jul.11, 2014", "summary": "We studied the crosstalk between tumor and endothelial cells to explore the role of tumor microenvironment on cancer growth and progression.  As part of our investigation, we showed that contact-dependent interaction of endothelial cells with breast tumor cells triggered the differential expression of a large number of genes in endothelium. Endothelial and MDA-MB231 cells were co-cultured together under serum- cytokine-free environment for 5 days followed by sorting endothelial cells and extracting RNA for microarray analysis. All conditions were made in triplicate.  Endothelial cells were obtained using the methods described in Seandel M. & Butler J.M., 2008. WCMC-Q Genomics Core", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-48786", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-48786/samples/"}