{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "human", "factors": [{"GSM1180240": {"MATERNAL BMI": "21.8", "GESTATIONAL AGE": "17+4", "FETAL SEX": "male"}}, {"GSM1180239": {"MATERNAL BMI": "22.7", "GESTATIONAL AGE": "18+4", "FETAL SEX": "female"}}, {"GSM1180238": {"MATERNAL BMI": "22.7", "GESTATIONAL AGE": "20+4", "FETAL SEX": "female"}}, {"GSM1180237": {"MATERNAL BMI": "20.7", "GESTATIONAL AGE": "18+6", "FETAL SEX": "male"}}, {"GSM1180236": {"MATERNAL BMI": "24", "GESTATIONAL AGE": "17+1", "FETAL SEX": "male"}}, {"GSM1180235": {"MATERNAL BMI": "23.6", "GESTATIONAL AGE": "18+0", "FETAL SEX": "female"}}, {"GSM1180234": {"MATERNAL BMI": "21.3", "GESTATIONAL AGE": "16+1", "FETAL SEX": "male"}}, {"GSM1180233": {"MATERNAL BMI": "18.9", "GESTATIONAL AGE": "16+5", "FETAL SEX": "female"}}, {"GSM1180232": {"MATERNAL BMI": "39.5", "GESTATIONAL AGE": "17+6", "FETAL SEX": "male"}}, {"GSM118023": {"MATERNAL BMI": "34.5", "GESTATIONAL AGE": "19+5", "FETAL SEX": "female"}}, {"GSM1180230": {"MATERNAL BMI": "33", "GESTATIONAL AGE": "20+1", "FETAL SEX": "female"}}, {"GSM1180229": {"MATERNAL BMI": "36.3", "GESTATIONAL AGE": "17+5", "FETAL SEX": "male"}}, {"GSM1180228": {"MATERNAL BMI": "30.4", "GESTATIONAL AGE": "16+0", "FETAL SEX": "male"}}, {"GSM1180227": {"MATERNAL BMI": "39.6", "GESTATIONAL AGE": "19+2", "FETAL SEX": "female"}}, {"GSM1180226": {"MATERNAL BMI": "33", "GESTATIONAL AGE": "16+2", "FETAL SEX": "male"}}, {"GSM1180225": {"MATERNAL BMI": "33.7", "GESTATIONAL AGE": "15+6", "FETAL SEX": "female"}}], "id": 2363, "ownerprofile_id": "arrayexpress_sid", "platform": 4, "summary_wrapped": "To investigate fetal gene expression in obese compared to lean women in the second trimester, by performing global gene expression...", "geo_gse_id": "E-GEOD-48521", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 3, "sample_count": 16, "tags": ["cell", "cerebral cortex", "cortex", "nervous system"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_id_plat": "E-GEOD-48521_A-AFFY-44", "slug": "maternal-obesity-affects-fetal-neurodevelopmental", "geo_gds_id": "", "name": "Maternal obesity affects fetal neurodevelopmental and metabolic gene expression", "created": "Jul.12, 2014", "summary": "To investigate fetal gene expression in obese compared to lean women in the second trimester, by performing global gene expression analysis of amniotic fluid (AF) cell-free RNA Analysis of paired data from obese cases and lean controls revealed differential expression of 205 genes. Functional analysis of differentially expressed genes suggested down-regulation of apoptosis in fetuses of obese women, particularly within nervous system pathways involving the cerebral cortex, and activation of pro-estrogenic, pro-inflammatory transcriptional regulators. Prospective whole transcriptome microarray study analyzing cell-free RNA in AF from obese cases and lean controls in the second trimester. Significantly differentially-regulated genes in fetuses of obese cases (N= 8) vs. matched lean controls (N = 8) were identified and functional analyses were performed. Tissue-specific differential gene expression in fetuses of obese women was also examined.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-48521", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-48521/samples/"}