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<biogps><data><item key="owner">ArrayExpress Uploader</item><item key="ownerprofile_id">arrayexpress_sid</item><item key="species">human</item><item key="factors"><item><item key="GSM1165979"><item key="STIMULATED WITH">PMA and ionomycin for 9hrs</item></item></item><item><item key="GSM1165978"><item key="STIMULATED WITH">none (unstimulated)</item></item></item><item><item key="GSM1165979"><item key="STIMULATED WITH">PMA and ionomycin for 9hrs</item></item></item><item><item key="GSM1165978"><item key="STIMULATED WITH">none (unstimulated)</item></item></item></item><item key="id">2390</item><item key="pop_total">0</item><item key="platform">4</item><item key="summary_wrapped">Human T-cell leukemia virus type 1 (HTLV-1) encodes HTLV-1 bZIP factor (HBZ), which is thought to be crucial for neoplastic and...</item><item key="geo_gse_id">E-GEOD-48029</item><item key="owner_profile">/profile/8773/arrayexpressuploader</item><item key="factor_count">1</item><item key="sample_count">4</item><item key="tags"><item>cell</item><item>genome</item><item>leukemia</item><item>t-cell leukemia</item></item><item key="lastmodified">Dec.12, 2014</item><item key="is_default">False</item><item key="geo_gds_id"/><item key="slug">expression-data-of-jurkat-cells-stably-expressing</item><item key="geo_id_plat">E-GEOD-48029_A-AFFY-44</item><item key="name">Expression data of Jurkat cells stably expressing HBZ with or without stimulation</item><item key="created">Jul.12, 2014</item><item key="summary">Human T-cell leukemia virus type 1 (HTLV-1) encodes HTLV-1 bZIP factor (HBZ), which is thought to be crucial for neoplastic and inflammatory diseases caused by HTLV-1. So, we analyzed the transcriptional profile of HBZ expressing cells and how HBZ affect the expression of apoptosis-related genes. We used microarrays to detail the effect of HTLV-1 bZIP factor (HBZ), which is encoded in the minus strand of HTLV-1 genome on gene expression. Especially how HBZ affect the expression of apoptosis-related genes. Jurkat cells stably expressing HBZ were stimulated with or without PMA and ionomycin for 9hours. Then  RNA extraction and hybridization on Affymetrix microarrays were performed.</item><item key="source">http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-48029</item><item key="sample_source">http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-48029/samples/</item></data></biogps>
